PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32489049-11 2020 Additionally, animal experiments showed that scutellarin significantly inhibited the growth of subcutaneous xenografts in nude mice, and down-regulated the mRNA expressions of CD133, Lgr5, Gli1, Ptch1, c-Myc, Ki-67, CK20 and Nanog as well as the protein levels of c-Myc, Gli1, Lgr5, CD133 and Ki-67 of xenografts in nude mice. scutellarin 45-56 MYC proto-oncogene, bHLH transcription factor Homo sapiens 202-207 32489049-10 2020 The in vitro experiments showed that scutellarin inhibited the growth, transformation and differentiation of HT-29 CSC cells, significantly down-regulated the mRNA levels of Lgr5, c-Myc, CK20 and Nanog in HT-29 CSC cells as well as the protein expression levels of c-Myc, Gli1 and Lgr5 in HT-29 CSC cells. scutellarin 37-48 MYC proto-oncogene, bHLH transcription factor Homo sapiens 180-185 32489049-10 2020 The in vitro experiments showed that scutellarin inhibited the growth, transformation and differentiation of HT-29 CSC cells, significantly down-regulated the mRNA levels of Lgr5, c-Myc, CK20 and Nanog in HT-29 CSC cells as well as the protein expression levels of c-Myc, Gli1 and Lgr5 in HT-29 CSC cells. scutellarin 37-48 MYC proto-oncogene, bHLH transcription factor Homo sapiens 265-270 32489049-11 2020 Additionally, animal experiments showed that scutellarin significantly inhibited the growth of subcutaneous xenografts in nude mice, and down-regulated the mRNA expressions of CD133, Lgr5, Gli1, Ptch1, c-Myc, Ki-67, CK20 and Nanog as well as the protein levels of c-Myc, Gli1, Lgr5, CD133 and Ki-67 of xenografts in nude mice. scutellarin 45-56 MYC proto-oncogene, bHLH transcription factor Homo sapiens 264-269