PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22822035-0	2012	Mechanistic studies on the absorption and disposition of scutellarin in humans: selective OATP2B1-mediated hepatic uptake is a likely key determinant for its unique pharmacokinetic characteristics.	scutellarin	57-68	solute carrier organic anion transporter family member 2B1	Homo sapiens	90-97	
25858254-8	2016	RESULTS: Our results showed that mulberrin, scutellarin, quercetin, and glycyrrhetinic acid were strong inhibitors of OATP2B1-mediate E3S uptake with IC50 values being 1.8, 2.0, 7.5, and 13.0 muM, which were comparable with their plasma concentrations in clinical trials.	scutellarin	44-55	solute carrier organic anion transporter family member 2B1	Homo sapiens	118-125	
22822035-7	2012	Among the major hepatic anion uptake transporters, organic anion-transporting polypeptide (OATP) 2B1 played a predominant role in the hepatic uptake of S-6-G and S-7-G and showed greater preference for S-7-G with higher affinity than S-6-G (K(m) values were 1.77 and 43.9 muM, respectively).	scutellarin	162-167	solute carrier organic anion transporter family member 2B1	Homo sapiens	51-100	
22822035-7	2012	Among the major hepatic anion uptake transporters, organic anion-transporting polypeptide (OATP) 2B1 played a predominant role in the hepatic uptake of S-6-G and S-7-G and showed greater preference for S-7-G with higher affinity than S-6-G (K(m) values were 1.77 and 43.9 muM, respectively).	scutellarin	202-207	solute carrier organic anion transporter family member 2B1	Homo sapiens	51-100	
22822035-8	2012	Considering the low intrinsic permeability of S-6-G and S-7-G and the role of OATP2B1 in the hepatic clearance of such compounds, the selective hepatic uptake of S-7-G mediated by OATP2B1 is likely a key determinant for the much lower systemic exposure of S-7-G than S-6-G in humans.	scutellarin	162-167	solute carrier organic anion transporter family member 2B1	Homo sapiens	180-187	
22822035-8	2012	Considering the low intrinsic permeability of S-6-G and S-7-G and the role of OATP2B1 in the hepatic clearance of such compounds, the selective hepatic uptake of S-7-G mediated by OATP2B1 is likely a key determinant for the much lower systemic exposure of S-7-G than S-6-G in humans.	scutellarin	162-167	solute carrier organic anion transporter family member 2B1	Homo sapiens	180-187