PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25073400-0	2014	In vivo effects of scutellarin on the activities of CYP1A2, CYP2C11, CYP2D1, and CYP3A1/2 by cocktail probe drugs in rats.	scutellarin	19-30	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	60-67	
25073400-1	2014	OBJECTIVE: To investigate the influence of scutellarin on the activities of CYP1A2, CYP2C11, CYP2D1, and CYP3A1/2 in rats in vivo.	scutellarin	43-54	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	84-91	
25073400-6	2014	The activity of CYP2C11 in rats was inhibited significantly after treatment with scutellarin by increased tolbutamide t1/2 (16.74%, P < 0.01), T(max) (116.87%, P < 0.05), C(max) (63.78%, P < 0.01) and AUC(0-infinity) (70.61%, P < 0.01) in the scutellarin-treated group compared with those of the blank control.	scutellarin	81-92	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	16-23	
25073400-6	2014	The activity of CYP2C11 in rats was inhibited significantly after treatment with scutellarin by increased tolbutamide t1/2 (16.74%, P < 0.01), T(max) (116.87%, P < 0.05), C(max) (63.78%, P < 0.01) and AUC(0-infinity) (70.61%, P < 0.01) in the scutellarin-treated group compared with those of the blank control.	scutellarin	255-266	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	16-23	
25073400-9	2014	CONCLUSION: Scutellarin could significantly inhibit CYP1A2, CYP2C11 and CYP3A1/2 activities in rats in vivo, but had no effects on the activity of CYP2D1.	scutellarin	12-23	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	60-67