PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30797149-9 2019 Of note, the activations of JNK, ERK, p38 and stat3 induced by cisplatin were strikingly attenuated in scutellarin-treated mice. scutellarin 103-114 mitogen-activated protein kinase 8 Mus musculus 28-31 29680917-0 2018 Scutellarin suppresses neuroinflammation via the inhibition of the AKT/NF-kappaB and p38/JNK pathway in LPS-induced BV-2 microglial cells. scutellarin 0-11 mitogen-activated protein kinase 8 Mus musculus 89-92 29680917-5 2018 Consistent with the inhibition of NF-kappaB, scutellarin inhibited the phosphorylation of p38, JNK, and AKT without affecting phosphorylation of ERK1/2 or PI3K in LPS-induced BV-2 cells. scutellarin 45-56 mitogen-activated protein kinase 8 Mus musculus 95-98 29680917-6 2018 Overall, the present study suggests that scutellarin inhibits the production of pro-inflammatory mediators via inhibition of the IKK-dependent NF-kappaB and p38/JNK signaling pathway, which inhibits microglia activation and exerts anti-inflammation, indicating its potential therapeutic effect for neurodegenerative and cerebrovascular diseases. scutellarin 41-52 mitogen-activated protein kinase 8 Mus musculus 161-164