PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31810113-0 2020 Dengzhan Shengmai capsules and their active component scutellarin prevent cognitive decline in APP/PS1 mice by accelerating Abeta aggregation and reducing oligomers formation. scutellarin 54-65 presenilin 1 Mus musculus 99-102 29642616-5 2018 After nine months of treatment in APP/PS1 double-transgenic mice, scutellarin significantly improves behavior, reduces soluble and insoluble Abeta levels in the brain and plasma, decreases Abeta plaque associated gliosis and levels of proinflammatory cytokines TNF-alpha and IL-6, attenuates neuroinflammation, displays anti-amyloidogenic effects, and highlights the beneficial effects of intervention on development or progression of AD-like neuropathology. scutellarin 66-77 presenilin 1 Mus musculus 38-41