PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30891776-9 2019 Scutellarin significantly reduced Bcl-2 interacting mediator of cell death (Bim), caspase-3, APO-1, CD95 (Fas), and Bax: Bcl-2-associated X (Bax) levels and activated Bcl-2: B-cell lymphoma-2 (Bcl-2). scutellarin 0-11 caspase 3 Rattus norvegicus 82-91 30106052-9 2018 Pretreatment with 10 or 50 muM scutellarin substantially increased viability, reduced the expression of NOX2 and caspase-3, increased the expression of connexin 43, and diminished the levels of reactive oxygen species in astrocytes subjected to ischemia-reperfusion. scutellarin 31-42 caspase 3 Rattus norvegicus 113-122 18442013-6 2007 These results demonstrate that scutellarin can protect PC12 cells from cobalt chloride induced apoptosis by scavenging ROS, inhibiting p38 phosphorylation, up-regulating Bcl-XL expression and decreasing caspase-3 activity, and may reduce the cellular damage in pathological conditions associated with hypoxia-mediated neuronal injury. scutellarin 31-42 caspase 3 Rattus norvegicus 203-212