PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20047331-4	2010	The imidazole-based 20 showed high CB(1) receptor affinity (48 nM) in combination with high CB(1)/CB(2) receptor subtype selectivity (>20-fold) and elicited equipotent AChE inhibitory activity as 1.	imidazole	4-13	acetylcholinesterase (Cartwright blood group)	Homo sapiens	171-175	
30711701-2	2019	All imidazole derivatives were tested for AChE and BChE inhibition and showed nanomolar activity similar to that of the test compound donepezil and higher than that of tacrine.	imidazole	4-13	acetylcholinesterase (Cartwright blood group)	Homo sapiens	42-46	
31968151-0	2020	Organocatalyzed solvent free and efficient synthesis of 2,4,5-trisubstituted imidazoles as potential acetylcholinesterase inhibitors for Alzheimer"s disease.	imidazole	56-87	acetylcholinesterase (Cartwright blood group)	Homo sapiens	101-121	
31968151-4	2020	Among this series of compounds 3m bearing one ethoxy and a hydroxyl group on the phenyl ring on 2,4,5-trisubstituted imidazoles  proved potent AChE inhibitor (102.56+-0.14).	imidazole	96-127	acetylcholinesterase (Cartwright blood group)	Homo sapiens	143-147	
31138650-6	2019	Here, we present room temperature X-ray structures of native and VX-phosphonylated hAChE with an imidazole-based oxime reactivator, RS-170B.	imidazole	97-106	acetylcholinesterase (Cartwright blood group)	Homo sapiens	83-88	
25835984-9	2015	One of the later imidazole aldoximes, RS-170B, was a 2-3-fold more effective reactivator of Y337A/F338A AChE than HI-6 due to the smaller imidazole ring, as indicated by computational molecular models, that affords a more productive angle of nucleophilic attack.	imidazole	17-26	acetylcholinesterase (Cartwright blood group)	Homo sapiens	104-108