PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34504305-7 2021 These effects were canceled by the addition of LDN193189, a specific inhibitor of Smad1/5 signaling. LDN 193189 47-56 SMAD family member 1 Homo sapiens 82-89 22452883-4 2012 Moreover, such phospho-Smad1/5-mediated rapamycin responses were blocked by LDN-193189 (a BMPRI kinase inhibitor) or Noggin (a BMP antagonist) in LNCaP prostate cancer cells. LDN 193189 76-86 SMAD family member 1 Homo sapiens 23-28 34896864-9 2022 The inhibition of Smad1/5/8 signaling by LDN193189 suppressed the SP600125-induced osteoblastic differentiation of HPDLSCs. LDN 193189 41-50 SMAD family member 1 Homo sapiens 18-27 34445177-5 2021 We show that ligands of the Activin and TGF-beta families, several ligand traps, and the SMAD1/5/8 signaling inhibitor LDN-193189 profoundly suppressed 3T3-L1 adipogenesis. LDN 193189 119-129 SMAD family member 1 Homo sapiens 89-98 34247314-7 2022 LDN-193189, an inhibitor of the BMP/Smad pathway, was used to explore the underlying effects of BMP/Smad signaling on the process of LLLT regulating the proliferation and osteogenesis of PDLSCs. LDN 193189 0-10 SMAD family member 1 Homo sapiens 36-40 25253675-7 2014 Similarly, selective inhibition of SMAD1/5/8 phosphorylation with LDN-193189 decreased HO formation and increased range of motion at the injury site in our burn model in vivo. LDN 193189 66-76 SMAD family member 1 Homo sapiens 35-42 25003810-9 2014 In addition, pretreatment with SB431542, LDN193189, or Noggin prevented Snail-induced Smad1 and Akt hyperactivation and reactivated GSK3beta. LDN 193189 41-50 SMAD family member 1 Homo sapiens 86-91