PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34776443-2 2022 OBJECTIVE: Using 18F-THK5351 as a tracer that binds to both tau and MAO-B, we investigated the changes in 18F-THK5351 accumulation patterns in AD continuum individuals with positive amyloid PET consisting of cognitively normal individuals (CNp), amnestic mild cognitive impairment (aMCI), and AD and cognitively normal individuals (CNn) with negative amyloid PET. THK5351 21-28 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 240-243 34776443-2 2022 OBJECTIVE: Using 18F-THK5351 as a tracer that binds to both tau and MAO-B, we investigated the changes in 18F-THK5351 accumulation patterns in AD continuum individuals with positive amyloid PET consisting of cognitively normal individuals (CNp), amnestic mild cognitive impairment (aMCI), and AD and cognitively normal individuals (CNn) with negative amyloid PET. THK5351 110-117 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 240-243