PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11677234-2 2002 Prostaglandin synthesis by cyclooxygenases-1 and -2 (COX-1 and COX-2) involves an initial oxygenation of arachidonic acid at C-11, followed by endoperoxide and cyclopentane ring formation, and then a second reaction with molecular oxygen in the S configuration at C-15. Cyclopentanes 160-172 prostaglandin-endoperoxide synthase 2 Homo sapiens 27-51