PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18678486-0 2008 Structure-activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350. Cyclopentanes 59-71 KRAS proto-oncogene, GTPase Homo sapiens 131-134 17845856-0 2007 Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs. Cyclopentanes 82-94 KRAS proto-oncogene, GTPase Homo sapiens 61-64 17845856-0 2007 Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs. Cyclopentanes 99-111 KRAS proto-oncogene, GTPase Homo sapiens 61-64 17845856-1 2007 Several highly potent novel HCV NS3 protease inhibitors have been developed from two inhibitor series containing either a P2 trisubstituted macrocyclic cyclopentane- or a P2 cyclopentene dicarboxylic acid moiety as surrogates for the widely used N-acyl-(4R)-hydroxyproline in the P2 position. Cyclopentanes 152-164 KRAS proto-oncogene, GTPase Homo sapiens 32-35