PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11728184-3 2001 This led us to design potential neuraminidase inhibitors in which the cyclopentane ring served as a scaffold for substituents (carboxylate, guanidino, acetamido, alkyl) that would interact with the four binding pockets of the neuraminidase active site at least as effectively as those of the established six-membered ring inhibitors such as DANA (2), zanamivir (3), and oseltamivir (4). Cyclopentanes 70-82 neuraminidase 1 Homo sapiens 32-45 11728184-3 2001 This led us to design potential neuraminidase inhibitors in which the cyclopentane ring served as a scaffold for substituents (carboxylate, guanidino, acetamido, alkyl) that would interact with the four binding pockets of the neuraminidase active site at least as effectively as those of the established six-membered ring inhibitors such as DANA (2), zanamivir (3), and oseltamivir (4). Cyclopentanes 70-82 neuraminidase 1 Homo sapiens 226-239