PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11726279-3	2001	We found that 1:1 stoichiometric binding of oxidized adrenodoxin to oxidized cytochrome P450scc complexed with cholesterol or 25-hydroxycholesterol caused shifts of the high-spin EPR signals of the heme moiety at 5 K. Such shifts were not observed for the low-spin EPR signals.	25-hydroxycholesterol	126-147	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	77-95	
26230055-2	2015	Addition of cholesterol 25-hydroperoxide to the enzymes CYP27A1 and CYP11A1 induced well-defined spectral changes while generating 25-hydroxycholesterol as the major product.	25-hydroxycholesterol	131-152	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	68-75	
8490050-7	1993	The rate of side-chain cleavage of 25-hydroxycholesterol by human cytochrome P-450scc in Tween-20 micelles was low, the highest rate being about 1% of the Vmax for cholesterol.	25-hydroxycholesterol	35-56	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	66-85	
9002660-2	1997	Human placental syncytiotrophoblasts were cultured for 48 h with estradiol, and P450scc activity was determined by the formation of progesterone from 25-hydroxycholesterol.	25-hydroxycholesterol	150-171	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	80-87	
1525044-4	1992	The role of different steroids in the regulation of P450 cholesterol side-chain cleavage enzyme (P450scc) and 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) was evaluated by measuring the conversion of P4 derived from unlabelled 25-hydroxycholesterol and from labelled pregnenolone, respectively.	25-hydroxycholesterol	231-252	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	97-104	
2598930-4	1989	25-Hydroxycholesterol proved to be a suitable substrate for determining the maximum rate of pregnenolone synthesis by cytochrome P-450scc in isolated mitochondria.	25-hydroxycholesterol	0-21	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	129-137	
3311719-11	1987	Insulin treatment did not affect P450 SCC activity, whereas IGF-I treatment significantly stimulated P450 SCC activity by 19-36%, as measured by the conversion of 25-hydroxycholesterol to progesterone.	25-hydroxycholesterol	163-184	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	101-109