PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33688584-3 2021 Comparing to those under trial/temporarily used antivirus drugs (i.e., umifenovir, lopinavir), ceftriaxone, cefotaxime, and cefuroxime show higher binding affinities to the N-terminal domain of N protein (N-NTD), C-terminal domain of N protein (N-CTD), and receptor-binding domain of S protein (S-RBD). Lopinavir 83-92 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 284-285 33531790-12 2021 This finding was of particular importance that other compounds including hydroxychloroquine sulphate, lopinavir and ivermectin could bind with the spike protein only by weak Vander wall bonds and no hydrogen bond formation was noticed. Lopinavir 102-111 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 147-152 33679150-5 2021 In this study, we docked five clinically used drug molecules, favipiravir, hydroxychloroquine, remdesivir, lopinavir, and ritonavir onto three target proteins, the receptor-binding domain of SARS-CoV-2 spike protein, SARS-CoV-2 main protease, and human furin protease. Lopinavir 107-116 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 202-207 32729392-4 2021 Molecular docking on 40 derivatives of standard drugs (Remdesivir, Lopinavir and Theophylline) led to the identification of R10, R2 and L9 as potential inhibitors of 3CLpro, PLpro and Spike protein, respectively. Lopinavir 67-76 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 184-189