PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31770146-2 2020 WHAT THIS ARTICLE TELLS US THAT IS NEW: In a cohort of 400 cardiac surgery patients, intraoperative plasma concentrations of F2-isoprostanes and isofurans (markers of oxidative damage) were independently associated with both increased postoperative delirium and increased plasma concentrations of ubiquitin carboxyl-terminal hydrolase isozyme L1, a marker of neuronal injury.The association between increased systemic markers of oxidative damage and increased neuronal injury was stronger in patients with elevated plasma S100 calcium-binding protein B, a marker of blood-brain barrier disruption. F2-Isoprostanes 125-140 S100 calcium binding protein B Homo sapiens 522-552 31770146-12 2020 The association between increased intraoperative F2-isoprostanes and isofurans and increased postoperative ubiquitin carboxyl-terminal hydrolase isozyme L1 was amplified in patients with elevated S100 calcium-binding protein B (P = 0.049). F2-Isoprostanes 49-64 S100 calcium binding protein B Homo sapiens 196-226