PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30094101-0 2018 Bufalin inhibits glycolysis-induced cell growth and proliferation through the suppression of Integrin beta2/FAK signaling pathway in ovarian cancer. bufalin 0-7 integrin subunit beta 2 Homo sapiens 93-107 30094101-5 2018 Mechanistically, bufalin exerted its anti-tumor effect by targeting ITGB2/FAK signaling pathway in vitro and in vivo, which could be rescued by the introduction of ITGB2 cDNA in ovarian cancer cells. bufalin 17-24 integrin subunit beta 2 Homo sapiens 68-73 30094101-5 2018 Mechanistically, bufalin exerted its anti-tumor effect by targeting ITGB2/FAK signaling pathway in vitro and in vivo, which could be rescued by the introduction of ITGB2 cDNA in ovarian cancer cells. bufalin 17-24 integrin subunit beta 2 Homo sapiens 164-169 30094101-6 2018 These findings provide evidence that bufalin inhibited cellular glycolysis-induced cell growth and proliferation through repression of the ITGB2/FAK pathway, indicating that bufalin may be developed as a chemotherapeutic agent to treat ovarian cancer. bufalin 37-44 integrin subunit beta 2 Homo sapiens 139-144 30094101-6 2018 These findings provide evidence that bufalin inhibited cellular glycolysis-induced cell growth and proliferation through repression of the ITGB2/FAK pathway, indicating that bufalin may be developed as a chemotherapeutic agent to treat ovarian cancer. bufalin 174-181 integrin subunit beta 2 Homo sapiens 139-144