PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30128000-3	2018	In the present study, it was demonstrated that bufalin inhibited cell proliferation, blocked the cell cycle in the G2/M phase, and reduced the metastasis of human RCC ACHN cells via the upregulation of p21waf/cip1 and E-cadherin and the downregulation of cyclin dependent kinase 1, cyclin B1, N-cadherin, and hypoxia-inducible factor-1alpha (HIF-1alpha).	bufalin	47-54	cyclin dependent kinase 1	Homo sapiens	255-280	
24218335-12	2014	The influence on the level of cylinB1, CDK1, and p21 was also observed after bufalin treatment, and the relationship between Hsp27 and the cell cycle-related proteins mentioned above deserves much more research.	bufalin	77-84	cyclin dependent kinase 1	Homo sapiens	39-43	
22858649-4	2012	In addition, bufalin induced G2/M phase arrest by reducing CDK1 activity.	bufalin	13-20	cyclin dependent kinase 1	Homo sapiens	59-63