PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19429444-2	2009	The cardiotonic steroid bufalin enhances vitamin D-induced differentiation of leukemia cells and VDR transactivation activity.	bufalin	24-31	vitamin D receptor	Homo sapiens	97-100	
19429444-10	2009	Bufalin-induced nuclear VDR expression was associated with histone acetylation and VDR recruitment to the CYP24A1 promoter in HL60 cells.	bufalin	0-7	vitamin D receptor	Homo sapiens	24-27	
19429444-10	2009	Bufalin-induced nuclear VDR expression was associated with histone acetylation and VDR recruitment to the CYP24A1 promoter in HL60 cells.	bufalin	0-7	vitamin D receptor	Homo sapiens	83-86	
19429444-11	2009	Thus, the Na(+),K(+)-ATPase inhibitor bufalin modulates VDR function through several mechanisms, including Erk MAP kinase activation and increased nuclear VDR expression.	bufalin	38-45	vitamin D receptor	Homo sapiens	56-59	
19429444-11	2009	Thus, the Na(+),K(+)-ATPase inhibitor bufalin modulates VDR function through several mechanisms, including Erk MAP kinase activation and increased nuclear VDR expression.	bufalin	38-45	vitamin D receptor	Homo sapiens	155-158	
19429444-4	2009	Bufalin in combination with 1,25(OH)(2)D(3) enhanced the expression of VDR target genes, such as CYP24A1 and cathelicidin antimicrobial peptide, and effectively induced differentiation phenotypes.	bufalin	0-7	vitamin D receptor	Homo sapiens	71-74	
19429444-7	2009	Interestingly, bufalin enhanced 1,25(OH)(2)D(3)-induced nuclear VDR expression.	bufalin	15-22	vitamin D receptor	Homo sapiens	64-67	
16183038-4	2005	Bufalin also augmented VDR activation by bile acid ligands, such as lithocholic acid and 3-ketocholanic acid.	bufalin	0-7	vitamin D receptor	Homo sapiens	23-26	
16183038-6	2005	Bufalin did not bind directly to VDR but did modulate the interaction of VDR and cofactors, such as steroid receptor coactivator-1 and nuclear receptor corepressor.	bufalin	0-7	vitamin D receptor	Homo sapiens	73-76	
16183038-7	2005	Bufalin treatment significantly increased the expression of an endogenous VDR target gene, CYP24, in kidney- and monocyte-derived cell lines treated with 1,25(OH)(2)D(3).	bufalin	0-7	vitamin D receptor	Homo sapiens	74-77	
16183038-9	2005	Bufalin may be a useful tool in the investigation of VDR regulation by membrane-originating cellular signals and of pathophysiological mechanisms linking VDR to cardiovascular dysfunction.	bufalin	0-7	vitamin D receptor	Homo sapiens	53-56	
16183038-9	2005	Bufalin may be a useful tool in the investigation of VDR regulation by membrane-originating cellular signals and of pathophysiological mechanisms linking VDR to cardiovascular dysfunction.	bufalin	0-7	vitamin D receptor	Homo sapiens	154-157