PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34376212-0 2021 Bufalin induces mitochondrial dysfunction and promotes apoptosis of glioma cells by regulating Annexin A2 and DRP1 protein expression. bufalin 0-7 utrophin Homo sapiens 110-114 34376212-8 2021 siRNA targeting Annexin A2 and the DRP1 protein inhibitor Mdivi-1 were used to confirm the targets of bufalin. bufalin 102-109 utrophin Homo sapiens 35-39 34376212-12 2021 CONCLUSIONS: Our research indicated that bufalin can cause Annexin A2 and DRP1 oligomerization on the surface of mitochondria and disrupt the mitochondrial division/fusion balance to induce U251 cell apoptosis. bufalin 41-48 utrophin Homo sapiens 74-78