PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28693242-9	2017	Therefore, bufalin may provide an effective therapeutic strategy for the safe treatment of human bladder cancers that are resistant to TRAIL.	bufalin	11-18	TNF superfamily member 10	Homo sapiens	135-140	
28693242-0	2017	Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis.	bufalin	0-7	TNF superfamily member 10	Homo sapiens	52-57	
30612454-0	2019	Bufalin Induces Apoptotic Cell Death in Human Nasopharyngeal Carcinoma Cells through Mitochondrial ROS and TRAIL Pathways.	bufalin	0-7	TNF superfamily member 10	Homo sapiens	107-112	
30612454-13	2019	Based on these findings, we suggest bufalin induced apoptotic cell death via caspase-dependent, mitochondria-dependent and TRAIL pathways in human nasopharyngeal carcinoma NPC-TW 076 cells.	bufalin	36-43	TNF superfamily member 10	Homo sapiens	123-128	
24710190-0	2014	Bufalin enhances TRAIL-induced apoptosis by redistributing death receptors in lipid rafts in breast cancer cells.	bufalin	0-7	TNF superfamily member 10	Homo sapiens	17-22	
24710190-4	2014	The results showed that bufalin enhanced TRAIL-induced apoptosis in MCF-7 and MDA-MB-231 breast cancer cells by activating the extrinsic apoptotic pathway.	bufalin	24-31	TNF superfamily member 10	Homo sapiens	41-46	
24710190-7	2014	Overall, these results indicate that bufalin enhanced TRAIL-induced apoptosis in breast cancer cells by the partial redistribution of DRs in lipid rafts.	bufalin	37-44	TNF superfamily member 10	Homo sapiens	54-59	
24710190-3	2014	In the present study, we explored the effect of bufalin on TRAIL-induced breast cancer cell apoptosis.	bufalin	48-55	TNF superfamily member 10	Homo sapiens	59-64	
21259053-4	2011	In the current study, we found that bufalin, bufotalin and gamabufotalin, key members of bufadienolides isolated from a traditional Chinese medicine ChanSu, significantly potentiated human breast cancer cells with different status of ER-alpha to apoptosis induction of TRAIL, as evidenced by enhanced Annexin V/FITC positive cells (apoptotic cells), cytoplasmic histone-associated-DNA-fragments, membrane permeability transition (MPT), caspases activation and PARP cleavage.	bufalin	36-43	TNF superfamily member 10	Homo sapiens	269-274	
22447040-9	2012	Both cell lines were dramatically sensitized to TRAIL-induced apoptosis by bufalin.	bufalin	75-82	TNF superfamily member 10	Homo sapiens	48-53	
23317181-7	2012	Bufalin, bufotalin and gamabufotalin, key bufadienolides, significantly sensitize human breast cancer cells with differing ER-alpha status to apoptosis induction by the TNF-related apoptosis-inducing ligand (TRAIL).	bufalin	0-7	TNF superfamily member 10	Homo sapiens	169-206	
23317181-7	2012	Bufalin, bufotalin and gamabufotalin, key bufadienolides, significantly sensitize human breast cancer cells with differing ER-alpha status to apoptosis induction by the TNF-related apoptosis-inducing ligand (TRAIL).	bufalin	0-7	TNF superfamily member 10	Homo sapiens	208-213