PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26463323-8 2015 The results of transwell migration assay showed that in the presence of HGF, afatinib plus bufalin combination therapy markedly decreased the number of invaded H1975 cells through the Matrigel chamber (48.98 +- 11.43), significantly lower than the 118.92 +- 37.29 of afatinib-treated or the 88.84 +- 19.53 of bufalin-treated cells (P < 0.05 for all). bufalin 91-98 hepatocyte growth factor Homo sapiens 72-75 26463323-0 2015 [Bufalin reverses hepatocyte growth factor-induced resistance to afatinib in H1975 lung cancer cells]. bufalin 1-8 hepatocyte growth factor Homo sapiens 18-42 26463323-1 2015 OBJECTIVE: To investigate the effects of bufalin in reversing hepatocyte growth factor (HGF)-induced resistance to afatinib in H1975 lung cancer cells, and explore its possible mechanism. bufalin 41-48 hepatocyte growth factor Homo sapiens 62-86 26463323-1 2015 OBJECTIVE: To investigate the effects of bufalin in reversing hepatocyte growth factor (HGF)-induced resistance to afatinib in H1975 lung cancer cells, and explore its possible mechanism. bufalin 41-48 hepatocyte growth factor Homo sapiens 88-91 26463323-8 2015 The results of transwell migration assay showed that in the presence of HGF, afatinib plus bufalin combination therapy markedly decreased the number of invaded H1975 cells through the Matrigel chamber (48.98 +- 11.43), significantly lower than the 118.92 +- 37.29 of afatinib-treated or the 88.84 +- 19.53 of bufalin-treated cells (P < 0.05 for all). bufalin 309-316 hepatocyte growth factor Homo sapiens 72-75 23533466-0 2013 Bufalin Reverses HGF-Induced Resistance to EGFR-TKIs in EGFR Mutant Lung Cancer Cells via Blockage of Met/PI3k/Akt Pathway and Induction of Apoptosis. bufalin 0-7 hepatocyte growth factor Homo sapiens 17-20 23533466-6 2013 Our studies showed that bufalin could reverse resistance to reversible and irreversible EGFR-TKIs induced by exogenous HGF in EGFR mutant lung cancer cells by inhibiting the Met/PI3K/Akt pathway and inducing death signaling. bufalin 24-31 hepatocyte growth factor Homo sapiens 119-122 23533466-5 2013 The purpose of this study was to determine whether bufalin, a major bioactive component of Venenum Bufonis, could reverse HGF-induced resistance to reversible and irreversible EGFR-TKIs in mutant lung cancer cells PC-9, HCC827, and H1975. bufalin 51-58 hepatocyte growth factor Homo sapiens 122-125