PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33530915-7 2021 After inhibiting autophagy, Bufalin significantly inhibited the protein expression of P-AKT, Cyclin D1, MMP-2, MMP-9 and VEGF in HCC-LM3 cells. bufalin 28-35 vascular endothelial growth factor A Homo sapiens 121-125 34496870-9 2021 The results demonstrated that the proangiogenic genes in HUVECs, such as VEGF, PDGFA, E-selectin and P-selectin, were downregulated by bufalin and that this downregulation was mediated by inhibition of the STAT3 pathway. bufalin 135-142 vascular endothelial growth factor A Homo sapiens 73-77 26782953-0 2016 Bufalin enhances anti-angiogenic effect of sorafenib via AKT/VEGF signaling. bufalin 0-7 vascular endothelial growth factor A Homo sapiens 61-65 29620259-0 2018 Synergistic anti-hepatoma effect of bufalin combined with sorafenib via mediating the tumor vascular microenvironment by targeting mTOR/VEGF signaling. bufalin 36-43 vascular endothelial growth factor A Homo sapiens 136-140 29620259-13 2018 In conclusion, the results revealed a synergistic anti-hepatoma effect of bufalin combined with sorafenib via affecting the tumor vascular microenvironment by targeting mTOR/VEGF signaling. bufalin 74-81 vascular endothelial growth factor A Homo sapiens 174-178 27634330-7 2016 Bufalin could downregulate the downstream target molecules of MMP-2, MMP-9, beta-catenin and VEGF in liver cancer cells by influencing the Gli1 and Gli3 expression of Hh signaling pathway, and upregulate the E-cadherin expression of liver cancer cells by influencing the Gli3 expression of Hh signaling pathway. bufalin 0-7 vascular endothelial growth factor A Homo sapiens 93-97 26782953-15 2016 Taken together, our findings demonstrated for the first time that bufalin can enhance anti-angiogenic effect of sorafenib via modulating the AKT/VEGF signaling pathway. bufalin 66-73 vascular endothelial growth factor A Homo sapiens 145-149 23949904-9 2015 Bufalin also suppressed protein levels of FAK and Rho A, VEGF, MEKK3, MKK7, and uPA and it diminished NF-kappaB translocation. bufalin 0-7 vascular endothelial growth factor A Homo sapiens 57-61