PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24925806-6	2014	While several inhibitors are available for caspase-1 blocking experiments, in this study we show effects of two commonly used caspase inhibitors: z-VAD-fmk and ac-YVAD-cmk on secretion of pro-inflammatory cytokines: IL-1beta, TNFalpha, IL-8 and IL-6 in whole blood stimulated with LPS.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	146-155	interleukin 6	Homo sapiens	245-249	
30206205-7	2018	TNFR2/ZVAD-induced production of IL-6 and IL-1beta was largely blocked in necroptosis-resistant MLKL- and RIPK3-deficient macrophages, whereas induction of A20 and TRAF1 remained unaffected.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	6-10	interleukin 6	Homo sapiens	33-37	
14627979-8	2003	Z-VAD-FMK also abrogates the inhibitory effect of PS-341 on IL-6-triggered signaling cascades.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	0-9	interleukin 6	Homo sapiens	60-64	
11960349-6	2002	It was shown that in AML cells cultured in the presence of Z-VAD-fmk, TGF-beta1 pretreatment resulted in a reduction of JAK1 phosphorylation upon IL-6 stimulation.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	59-68	interleukin 6	Homo sapiens	146-150