PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10200549-8 1999 Following IL-3 withdrawal, the caspase inhibitors z-VAD.fmk and boc-asp(OMe)fluoromethylketone (boc-asp.fmk) prevented the cleavage and activation of caspase-3, the breakdown of lamin B1 and partially mitigated PARP degradation. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 50-59 interleukin 3 Mus musculus 10-14 20125124-1 2010 Interleukin-3 (IL-3) deprivation of the mouse pro-B cell line Ba/F3 induces cell death that is abrogated by B-cell lymphoma 2 (Bcl-2) overexpression, but remains unaffected by the pan-caspase inhibitor carbobenzoxy-valyl-analyl-aspartyl-[O-methyl]-fluoromethylketone (zVAD-fmk). benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 268-276 interleukin 3 Mus musculus 0-19 20125124-6 2010 Interestingly, knockdown of HtrA2/Omi afforded protection against IL-3 withdrawal-induced death in the presence of zVAD-fmk, demonstrating a role for HtrA2/Omi in caspase-independent cell death during growth factor withdrawal by cleaving RIP1. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 115-123 interleukin 3 Mus musculus 66-70 12148244-6 2002 zVAD-fmk, a broad caspase inhibitor, prevented chromatin condensation and fragmentation, but not cell death, suggesting that IL-3 deprivation induces a cell death program in which the caspases are dispensable. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 0-8 interleukin 3 Mus musculus 125-129 9202146-3 1997 Cell death by IL-3 withdrawal is inhibited by the caspase-inhibitor ZVAD-fmk, but not DEVD-fmk or YVAD-cmk. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 68-76 interleukin 3 Mus musculus 14-18