PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20428991-3 2010 This tissue showed low sensitivity to NCX inhibitor KB-R7943 (IC50, 57 +/- 2 microM), although a complete relaxation was obtained by NCX inhibition at 100 microM. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 52-60 T cell leukemia homeobox 2 Homo sapiens 38-41 17401656-8 2007 In contrast, treatment of KBR7943 or thapsigargin, antagonists to Na/Ca Exchanger (NCX) and Sarco/Endoplasmic reticulum Ca(2+)-ATPase (SERCA), respectively, did not elicit any changes in [Ca(2+)](i). 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 26-33 T cell leukemia homeobox 2 Homo sapiens 83-86 15010500-10 2004 By contrast, KB-R7943 [(2-[2-[4-nitrobenzyloxy]phenyl]ethyl)-isothioureamethanesulfonate] preferentially blocks sodium-dependent calcium influx by NCX (reverse mode) and was nontoxic to glioma cells. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 13-21 T cell leukemia homeobox 2 Homo sapiens 147-150 17035299-9 2007 HAIR/REOX triggered a secondary, sustained rise in intracellular Ca(2+) that was attenuated by reversal NCX inhibitor KB-R7943. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 118-126 T cell leukemia homeobox 2 Homo sapiens 104-107 16960425-5 2006 As an NCX inhibitor, we preferred to use SEA0400 instead of KB-R 7943. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 60-69 T cell leukemia homeobox 2 Homo sapiens 6-9 15060069-8 2004 NCLX activity is only partially inhibited by the NCX inhibitor, KB-R7943. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 64-72 T cell leukemia homeobox 2 Homo sapiens 49-52 12810056-7 2003 Application of Ni(2+) or KBR7943 to block Na(+)-Ca(2+) exchanger (NCX) also inhibited [Ca(2+)](i) oscillations. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 25-32 T cell leukemia homeobox 2 Homo sapiens 66-69 14659804-5 2003 Force but not [Na(+)](i) increase was abolished by inhibition of reverse Na(+)/Ca(2+) exchange (NCX) with the inhibitor KB-R7943. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 120-128 T cell leukemia homeobox 2 Homo sapiens 96-99 32794054-7 2020 In those with pacing-induced VTs, KB-R7943 (10 muM, a Na+-Ca2+ exchanger inhibitor, NCX inhibitor) significantly reduced the occurrence of VTs from 100.0 to 20.0% (15/15 to 3/15 episodes, p < 0.001). 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 34-42 T cell leukemia homeobox 2 Homo sapiens 84-87 25148264-1 2015 This study was designed to investigate the protective effects of KB-R7943, an inhibitor of sodium/calcium exchanger (NCX) on endothelial dysfunction induced by high glucose in endothelial cells. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 65-73 T cell leukemia homeobox 2 Homo sapiens 117-120