PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32900381-7 2020 For glycosphingolipids (GSLs), Globo H ceramide, an important tumor-associated GSL which is being actively investigated as a target for new cancer immunotherapies, will be used to demonstrate how glycan structure plays a significant role in enhancing angiogenesis in tumor microenvironments. Ceramides 39-47 cathepsin A Homo sapiens 24-27 26609196-7 2015 These observations suggest that the very long fatty acid chains of ceramide are critical for GSL-mediated outside-in signaling. Ceramides 67-75 cathepsin A Homo sapiens 93-96 30030471-3 2018 The method provides the composition and sequence of the glycan, as well as variations in the ceramide portion of the GSL. Ceramides 93-101 cathepsin A Homo sapiens 117-120 31058489-3 2019 Here, we describe the development of a novel and high-throughput-compatible workflow for the analysis of GSL-derived glycans based on ceramide glycanase digestion, 8-aminopyrene-1,3,6-trisulfonic acid (APTS) labeling, and multiplexed capillary gel electrophoresis coupled to laser-induced fluorescence detection (xCGE-LIF). Ceramides 134-142 cathepsin A Homo sapiens 105-108 25151392-2 2014 Each GSL contains a complex carbohydrate chain linked to a ceramide moiety that anchors the molecule to biomembranes. Ceramides 59-67 cathepsin A Homo sapiens 5-8 20213680-4 2010 The GSL structure is characterized by two entities: a hydrophilic glycan and a hydrophobic ceramide moiety. Ceramides 91-99 cathepsin A Homo sapiens 4-7 21549856-4 2011 The ceramide variability caused by the diversity of the long-chain amino alcohol and the fatty acid, which both may vary in chain length, degree of unsaturation, and type and number of substituents, further contributes to the increasing number of possible GSL species. Ceramides 4-12 cathepsin A Homo sapiens 256-259