PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21671327-3 2011 We synthesized a biotinylated photoaffinity derivative of triptolide, and used it to identify dCTP pyrophosphatase 1 (DCTPP1) as a triptolide-interacting protein. triptolide 58-68 dCTP pyrophosphatase 1 Homo sapiens 118-124 21671327-3 2011 We synthesized a biotinylated photoaffinity derivative of triptolide, and used it to identify dCTP pyrophosphatase 1 (DCTPP1) as a triptolide-interacting protein. triptolide 131-141 dCTP pyrophosphatase 1 Homo sapiens 118-124 21671327-4 2011 Free triptolide interacts directly with recombinant DCTPP1, and inhibits the enzymatic activity of this protein. triptolide 5-15 dCTP pyrophosphatase 1 Homo sapiens 52-58 21671327-5 2011 Triptolide is thus the first dCTP pyrophosphatase inhibitor identified, and DCTPP1 is a biophysically validated target of triptolide. triptolide 122-132 dCTP pyrophosphatase 1 Homo sapiens 76-82