PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15390118-3	2004	Pre-treatment of microglia with TNF reduced in a dose- and time-dependent manner cAMP accumulation induced by forskolin (FSK), in the presence of the phosphodiesterase inhibitor 3-isobutyl-1-methyl-xanthine (IBMX).	Colforsin	110-119	tumor necrosis factor-like	Rattus norvegicus	32-35	
2373711-2	1990	Both forskolin-induced and tumor necrosis factor (TNF)-induced PLA2 release responses were almost completely blocked by 10 and 100 nM dexamethasone, respectively, as assayed by protein blotting and PLA2 activity assays.	Colforsin	5-14	tumor necrosis factor-like	Rattus norvegicus	50-53	
15390118-3	2004	Pre-treatment of microglia with TNF reduced in a dose- and time-dependent manner cAMP accumulation induced by forskolin (FSK), in the presence of the phosphodiesterase inhibitor 3-isobutyl-1-methyl-xanthine (IBMX).	Colforsin	121-124	tumor necrosis factor-like	Rattus norvegicus	32-35	
15390118-6	2004	The target of TNF appeared to be adenylyl cyclase, whose ability to synthesize cAMP was markedly reduced (up to 50%) in membranes prepared from TNF-treated microglial cells, both in basal conditions and after stimulation with FSK.	Colforsin	226-229	tumor necrosis factor-like	Rattus norvegicus	14-17	
15390118-6	2004	The target of TNF appeared to be adenylyl cyclase, whose ability to synthesize cAMP was markedly reduced (up to 50%) in membranes prepared from TNF-treated microglial cells, both in basal conditions and after stimulation with FSK.	Colforsin	226-229	tumor necrosis factor-like	Rattus norvegicus	144-147	
15390118-8	2004	The same inhibitors also markedly prevented the reduction of FSK-evoked cAMP accumulation by TNF, suggesting the involvement of NFkappaB in the regulation of adenylyl cyclase by TNF in microglia.	Colforsin	61-64	tumor necrosis factor-like	Rattus norvegicus	93-96	
15390118-8	2004	The same inhibitors also markedly prevented the reduction of FSK-evoked cAMP accumulation by TNF, suggesting the involvement of NFkappaB in the regulation of adenylyl cyclase by TNF in microglia.	Colforsin	61-64	tumor necrosis factor-like	Rattus norvegicus	178-181