PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2749584-1 1989 Forskolin, a plant (Coleus forskohlii) diterpene, inhibits ADP-induced (human: IC50, 2.3 +/- 1.0 microM; rat: IC50, 1.2 +/- 0.5 microM) and collagen-induced (human: IC50, 2.4 +/- 1.2 microM; rat: 0.6 +/- 0.2 microM) platelet aggregation in human and rat platelet-rich plasma (PRP). Colforsin 0-9 proline rich protein 2-like 1 Rattus norvegicus 276-279 2749584-4 1989 If the plasma Ado is degraded by pretreatment of PRP with adenosine deaminase (ADA), forskolin inhibition on platelet aggregation is reduced by 2-4 fold both in human and rat blood. Colforsin 85-94 proline rich protein 2-like 1 Rattus norvegicus 49-52 2749584-6 1989 Similar potentiated forskolin effect (IC50, 0.53 microM) is seen if the ADA-treated human PRP is replenished with a low level of Ado (50 nM) after ADA inactivation by dCF and Ado-uptake blockade by dilazep. Colforsin 20-29 proline rich protein 2-like 1 Rattus norvegicus 90-93 2749584-8 1989 Forskolin is 2-4 fold more inhibitory in rat PRP than in human PRP, partially due to the presence of higher levels of Ado in the rat plasma. Colforsin 0-9 proline rich protein 2-like 1 Rattus norvegicus 45-48 2749584-8 1989 Forskolin is 2-4 fold more inhibitory in rat PRP than in human PRP, partially due to the presence of higher levels of Ado in the rat plasma. Colforsin 0-9 proline rich protein 2-like 1 Rattus norvegicus 63-66 2847950-5 1988 The hybrid cells exhibited induced proline-rich protein mRNA synthesis when incubated with either dibutyryl cyclic AMP or forskolin. Colforsin 122-131 proline rich protein 2-like 1 Rattus norvegicus 35-55