PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14502440-3	2003	CFTR activity was measured using the (125I) iodide efflux technique and whole-cell patch-clamp recording in response to either forskolin or xanthine derivatives.	Colforsin	127-136	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	0-4	
14502435-5	2003	However, in the presence of 10 microM forskolin, NS004 stimulated G551D-CFTR activity in a dose-dependent manner with an EC(50) approximately 1.5 microM.	Colforsin	38-47	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	72-76	
17578899-3	2007	In whole-cell patch-clamp experiments of Chinese hamster ovary (CHO) cells expressing WT-CFTR, we recorded rapid and reversible inhibition of forskolin-activated CFTR currents in the presence of the adducts 5a and 8a,b at 10 pM concentrations.	Colforsin	142-151	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	89-93	
17578899-3	2007	In whole-cell patch-clamp experiments of Chinese hamster ovary (CHO) cells expressing WT-CFTR, we recorded rapid and reversible inhibition of forskolin-activated CFTR currents in the presence of the adducts 5a and 8a,b at 10 pM concentrations.	Colforsin	142-151	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	162-166	
14502440-8	2003	Furthermore, CFTR activation by forskolin or IBMX failed to promote [Ca2+]i increase, suggesting that CFTR activation did not generate an ATP release large enough to stimulate P2Y2 receptors.	Colforsin	32-41	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	13-17	
8661502-4	1996	In the cell-attached configuration with 100 mM Mg middle dot ATP or Tris middle dot ATP solution in the pipette and 140 mM NaCl in the bath, exposing cells to forskolin caused the activation of a low-conductance channel having kinetics resembling those of CFTR.	Colforsin	159-168	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	256-260	
12181609-2	2002	In wild-type CHO cells, after exposure to 2.5 microM forskolin, 25 microM genistein induced a further 2-fold and rapid increase of the forskolin-activated CFTR current.	Colforsin	53-62	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	155-159	
12181609-2	2002	In wild-type CHO cells, after exposure to 2.5 microM forskolin, 25 microM genistein induced a further 2-fold and rapid increase of the forskolin-activated CFTR current.	Colforsin	135-144	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	155-159	
12071471-6	2002	In Chinese hamster ovary cells expressing both the cystic fibrosis transmembrane conductance regulator chloride channel and P2.6 receptor, melatonin counteracted the forskolin induced activation of the channel.	Colforsin	166-175	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	51-102	
10501833-5	1999	The transient [Ca(2+)](i) increase produced by ATP or UTP could be mimicked by activation of CFTR with forskolin (20 microm) in CHO-CFTR confluent monolayers.	Colforsin	103-112	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	93-97	
10501833-5	1999	The transient [Ca(2+)](i) increase produced by ATP or UTP could be mimicked by activation of CFTR with forskolin (20 microm) in CHO-CFTR confluent monolayers.	Colforsin	103-112	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	132-136	
10501833-8	1999	(100 microm), and with hexokinase (0.28 U/mg) inhibited the [Ca(2+)](i) response to forskolin in CHO-CFTR infected cells.	Colforsin	84-93	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	101-105	
9306012-7	1997	Fsk and IBMX depolarized wt-CFTR-expressing CHO cells significantly (from -40 +/- 1.5 to -32 +/- 1.6 mV, n = 41) and enhanced Gm strongly from 5.0 +/- 0.9 to 36 +/- 3.9 nS (n = 65).	Colforsin	0-3	cystic fibrosis transmembrane conductance regulator	Cricetulus griseus	28-32