PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17202481-2 2007 The circadian peak of VP gene transcription in the SCN in vitro is completely blocked by a 2 h exposure to tetrodotoxin (TTX) in the culture medium, and this TTX inhibition of VP gene transcription is reversed by exposure of the SCN to either forskolin or potassium depolarization. Colforsin 243-252 arginine vasopressin Rattus norvegicus 22-24 17202481-2 2007 The circadian peak of VP gene transcription in the SCN in vitro is completely blocked by a 2 h exposure to tetrodotoxin (TTX) in the culture medium, and this TTX inhibition of VP gene transcription is reversed by exposure of the SCN to either forskolin or potassium depolarization. Colforsin 243-252 arginine vasopressin Rattus norvegicus 176-178 10794664-4 2000 The effect of vasopressin can be mimicked by either forskolin (1-5 microM) or 8-bromo-cAMP/dibutyryl-cAMP (8-Br-cAMP/DBcAMP) (200-500 microM). Colforsin 52-61 arginine vasopressin Rattus norvegicus 14-25 14614081-3 2003 AVP heteronuclear (hn) RNA, an indicator for gene transcription, was induced in the PVN with incubation of forskolin as reported previously, and AVP mRNA was increased by forskolin in the presence of the gene transcription inhibitor 5,6-dichloro-1-D-ribofuranosylbenzimidazole (DRB). Colforsin 107-116 arginine vasopressin Rattus norvegicus 0-3 14614081-3 2003 AVP heteronuclear (hn) RNA, an indicator for gene transcription, was induced in the PVN with incubation of forskolin as reported previously, and AVP mRNA was increased by forskolin in the presence of the gene transcription inhibitor 5,6-dichloro-1-D-ribofuranosylbenzimidazole (DRB). Colforsin 171-180 arginine vasopressin Rattus norvegicus 0-3 14614081-3 2003 AVP heteronuclear (hn) RNA, an indicator for gene transcription, was induced in the PVN with incubation of forskolin as reported previously, and AVP mRNA was increased by forskolin in the presence of the gene transcription inhibitor 5,6-dichloro-1-D-ribofuranosylbenzimidazole (DRB). Colforsin 171-180 arginine vasopressin Rattus norvegicus 145-148 11606471-4 2001 Forskolin-induced AVP hnRNA expression was unaffected by blockage of neurotransmission by the sodium channel inhibitor, tetrodotoxin, indicating that forskolin acts directly on AVP cells in the PVN. Colforsin 150-159 arginine vasopressin Rattus norvegicus 177-180 11606471-5 2001 Dual staining in situ hybridization of forskolin-stimulated hypothalamic sections using both radio labeled AVP hnRNA and digoxigenin-labeled CRH mRNA probes revealed colocalization of both transcripts, indicating AVP hnRNA is expressed in the parvocellular neurons. Colforsin 39-48 arginine vasopressin Rattus norvegicus 107-110 11606471-5 2001 Dual staining in situ hybridization of forskolin-stimulated hypothalamic sections using both radio labeled AVP hnRNA and digoxigenin-labeled CRH mRNA probes revealed colocalization of both transcripts, indicating AVP hnRNA is expressed in the parvocellular neurons. Colforsin 39-48 arginine vasopressin Rattus norvegicus 213-216 11573977-1 2001 Differential vasopressin (VP) gene expression and oxytocin (OT) gene expression were observed in hypothalamic cultures derived from 14-day-old rat fetuses, with VP but not OT being induced by treatment with forskolin and 3-isobutyl-1-methylxanthine. Colforsin 207-216 arginine vasopressin Rattus norvegicus 13-24 11573977-1 2001 Differential vasopressin (VP) gene expression and oxytocin (OT) gene expression were observed in hypothalamic cultures derived from 14-day-old rat fetuses, with VP but not OT being induced by treatment with forskolin and 3-isobutyl-1-methylxanthine. Colforsin 207-216 arginine vasopressin Rattus norvegicus 161-163 14614081-6 2003 However, when the hypothalamic slices were treated with forskolin, dexamethasone decreased AVP mRNA expression even in the presence of DRB and/or TTX. Colforsin 56-65 arginine vasopressin Rattus norvegicus 91-94 14614081-7 2003 Furthermore, AVP hnRNA expression induced by forskolin was attenuated by dexamethasone treatment in the presence of TTX. Colforsin 45-54 arginine vasopressin Rattus norvegicus 13-16 12399408-5 2002 In the presence of TTX, the adenylate cyclase stimulator, forskolin, increased AVP transcription in the SCN. Colforsin 58-67 arginine vasopressin Rattus norvegicus 79-82 11606471-2 2001 While AVP heteronuclear (hn) RNA was not detected in the PVN under basal conditions, a marked induction of AVP hnRNA was observed after 2 and 3 h incubation of slices with forskolin. Colforsin 172-181 arginine vasopressin Rattus norvegicus 6-9 11606471-2 2001 While AVP heteronuclear (hn) RNA was not detected in the PVN under basal conditions, a marked induction of AVP hnRNA was observed after 2 and 3 h incubation of slices with forskolin. Colforsin 172-181 arginine vasopressin Rattus norvegicus 107-110 11606471-4 2001 Forskolin-induced AVP hnRNA expression was unaffected by blockage of neurotransmission by the sodium channel inhibitor, tetrodotoxin, indicating that forskolin acts directly on AVP cells in the PVN. Colforsin 0-9 arginine vasopressin Rattus norvegicus 18-21 11606471-4 2001 Forskolin-induced AVP hnRNA expression was unaffected by blockage of neurotransmission by the sodium channel inhibitor, tetrodotoxin, indicating that forskolin acts directly on AVP cells in the PVN. Colforsin 0-9 arginine vasopressin Rattus norvegicus 177-180 11606471-4 2001 Forskolin-induced AVP hnRNA expression was unaffected by blockage of neurotransmission by the sodium channel inhibitor, tetrodotoxin, indicating that forskolin acts directly on AVP cells in the PVN. Colforsin 150-159 arginine vasopressin Rattus norvegicus 18-21 8812149-3 1996 The cultures were maintained in either control medium or medium containing the cAMP elevating drugs, IBMX (3-isobutyl-1-methylxanthine), and forskolin for 23 or 30 days of culture to induce VP synthesis and secretion. Colforsin 141-150 arginine vasopressin Rattus norvegicus 190-192 10780975-6 2000 In arteries activated by vasopressin, the adenylyl cyclase activator forskolin (3 microM) induced a maximum relaxation and a return of [Ca(2+)](i) to resting levels. Colforsin 69-78 arginine vasopressin Rattus norvegicus 25-36 8812149-5 1996 Administration of VP mRNA to the cultures treated continuously with IBMX and forskolin also resulted in a small increase in VP secretion which did not reach significance after either 6 or 24 h. When cultures prepared with continuous I/F were exposed to antisense VP mRNA, VP secretion into the media was decreased by 58%, and VP immunoreactive perikayra were difficult to observe. Colforsin 77-86 arginine vasopressin Rattus norvegicus 18-20 8812149-5 1996 Administration of VP mRNA to the cultures treated continuously with IBMX and forskolin also resulted in a small increase in VP secretion which did not reach significance after either 6 or 24 h. When cultures prepared with continuous I/F were exposed to antisense VP mRNA, VP secretion into the media was decreased by 58%, and VP immunoreactive perikayra were difficult to observe. Colforsin 77-86 arginine vasopressin Rattus norvegicus 124-126 8812149-5 1996 Administration of VP mRNA to the cultures treated continuously with IBMX and forskolin also resulted in a small increase in VP secretion which did not reach significance after either 6 or 24 h. When cultures prepared with continuous I/F were exposed to antisense VP mRNA, VP secretion into the media was decreased by 58%, and VP immunoreactive perikayra were difficult to observe. Colforsin 77-86 arginine vasopressin Rattus norvegicus 124-126 8812149-5 1996 Administration of VP mRNA to the cultures treated continuously with IBMX and forskolin also resulted in a small increase in VP secretion which did not reach significance after either 6 or 24 h. When cultures prepared with continuous I/F were exposed to antisense VP mRNA, VP secretion into the media was decreased by 58%, and VP immunoreactive perikayra were difficult to observe. Colforsin 77-86 arginine vasopressin Rattus norvegicus 124-126 8812149-5 1996 Administration of VP mRNA to the cultures treated continuously with IBMX and forskolin also resulted in a small increase in VP secretion which did not reach significance after either 6 or 24 h. When cultures prepared with continuous I/F were exposed to antisense VP mRNA, VP secretion into the media was decreased by 58%, and VP immunoreactive perikayra were difficult to observe. Colforsin 77-86 arginine vasopressin Rattus norvegicus 124-126 19215430-5 1990 Treatment of cultures with forskolin and/or the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (IBMX), both of which result in elevated intracellular cyclic AMP levels, increased the numbers of vasopressin-expressing cells up to 10-fold. Colforsin 27-36 arginine vasopressin Rattus norvegicus 203-214 7689952-6 1993 IBMX and forskolin treatment also resulted in detectable release of VP into the culture medium, which increased from 1.4 +/- 0.15 pg/ml at 11 days to 8.4 +/- 0.6 pg/ml after 32 days of drug treatment. Colforsin 9-18 arginine vasopressin Rattus norvegicus 68-70 1355050-2 1992 Forskolin stimulated the VP mRNA content and peptide secretion 2.6-fold and induced an increase in the poly(A) tail length of approximately 90 nucleotides. Colforsin 0-9 arginine vasopressin Rattus norvegicus 25-27 8779872-3 1996 cAMP-elevating agents, 3-isobutyl-1-methylxanthine (200 microM) and forskolin (25 microM), in combination (I-F) maintained NP synthesis and VP secretion in 19-day cultures. Colforsin 68-77 arginine vasopressin Rattus norvegicus 140-142 7521513-6 1994 Angiotensin II and arginine-vasopressin, acknowledged agonists for protein kinase C, elicited production of NO by forskolin-treated smooth muscle cells. Colforsin 114-123 arginine vasopressin Rattus norvegicus 28-39 7681263-4 1993 The action of AVP on low-conductance K+ channel activity was mimicked by simultaneous application of forskolin and 3-isobutyl-1-methylxanthine. Colforsin 101-110 arginine vasopressin Rattus norvegicus 14-17 1737959-2 1992 Both forskolin and PMA (phorbol 12-myristate 13-acetate) increased CRF, AVP and oxytocin release, while dexamethasone and aldosterone only reduced basal secretion of CRF. Colforsin 5-14 arginine vasopressin Rattus norvegicus 72-75 1737959-3 1992 Both steroids also inhibited forskolin-induced CRF, AVP and oxytocin responses to PMA. Colforsin 29-38 arginine vasopressin Rattus norvegicus 52-55 2545302-0 1989 Facilitation by forskolin of electrically evoked vasopressin release in vitro requires bursting pattern of stimulation. Colforsin 16-25 arginine vasopressin Rattus norvegicus 49-60 2168530-3 1990 Forskolin elicited a 3-fold greater increase in cyclic AMP in the neural lobe than in the supraoptic nucleus and enhanced the sensitivity of the tissues to both vasopressin and oxytocin. Colforsin 0-9 arginine vasopressin Rattus norvegicus 161-172 2545302-1 1989 Electrically stimulated release of vasopressin from isolated rat neurohypophysis was measured in the presence and absence of forskolin. Colforsin 125-134 arginine vasopressin Rattus norvegicus 35-46 2545302-2 1989 Forskolin inhibited the release of vasopressin evoked by continuous stimulation at constant frequency, and enhanced the release evoked by trains of pulses separated by silent intervals. Colforsin 0-9 arginine vasopressin Rattus norvegicus 35-46 3007735-3 1986 Addition of vasopressin to these cells inhibited beta adrenergic agonist- and forskolin-stimulated cAMP accumulation by 30 to 40% and by 25 to 35%, respectively. Colforsin 78-87 arginine vasopressin Rattus norvegicus 12-23 2566191-6 1989 In contrast, vasopressin in concentrations as low as 0.025-0.25 U/liter decreased the secretory effects of EFS (55-75%) and carbachol (85%), but had no effect on cAMP-dependent secretion elicited either by VIP or forskolin. Colforsin 213-222 arginine vasopressin Rattus norvegicus 13-24 2995530-3 1985 Two chemically dissimilar inhibitors of calmodulin, namely trifluoperazine and N-(6-amino-hexyl)-5-chloro-1-naphthalenesulphonamide (W-7), attenuated the AVP-, PGE2- and forskolin-stimulated cellular production of cyclic AMP in a dose-related manner. Colforsin 170-179 arginine vasopressin Rattus norvegicus 154-157 2995530-6 1985 Since forskolin directly activates adenylate cyclase at a site of the catalytic unit and the cellular action of AVP to activate adenylate cyclase is mediated through receptor-guanine nucleotide regulatory-catalytic units, the present study indicates calmodulin regulation of basal, AVP-, PGE2- and forskolin-activated adenylate cyclase in the papillary collecting tubule cells. Colforsin 298-307 arginine vasopressin Rattus norvegicus 112-115 2995530-6 1985 Since forskolin directly activates adenylate cyclase at a site of the catalytic unit and the cellular action of AVP to activate adenylate cyclase is mediated through receptor-guanine nucleotide regulatory-catalytic units, the present study indicates calmodulin regulation of basal, AVP-, PGE2- and forskolin-activated adenylate cyclase in the papillary collecting tubule cells. Colforsin 6-15 arginine vasopressin Rattus norvegicus 112-115 26503226-10 2015 The forskolin induced increase in Creb3l1 expression was diminished by combined treatment with dexamethasone, and, in vivo, intraperitoneal dexamethasone injection blunted the increase in Creb3l1 and Avp expression induced by hyperosmotic stress. Colforsin 4-13 arginine vasopressin Rattus norvegicus 200-203 3000838-6 1985 Since forskolin is recognized as activating adenylate cyclase at one step of the catalytic component and the cellular action of AVP to activate adenylate cyclase is mediated through receptor-catalytic component, the present study indicates calmodulin regulation of basal, AVP-, PGE2- and forskolin-activated adenylate cyclase in the papillary collecting tubule cells. Colforsin 6-15 arginine vasopressin Rattus norvegicus 272-275 3000838-6 1985 Since forskolin is recognized as activating adenylate cyclase at one step of the catalytic component and the cellular action of AVP to activate adenylate cyclase is mediated through receptor-catalytic component, the present study indicates calmodulin regulation of basal, AVP-, PGE2- and forskolin-activated adenylate cyclase in the papillary collecting tubule cells. Colforsin 288-297 arginine vasopressin Rattus norvegicus 128-131 2992649-0 1985 Forskolin: its effects on potassium-evoked release of vasopressin from the rat neurohypophysis. Colforsin 0-9 arginine vasopressin Rattus norvegicus 54-65 2992649-2 1985 A low concentration of forskolin (1 microM), added before stimulation, enhanced the potassium-evoked release of vasopressin throughout two successive 5 min periods of stimulation. Colforsin 23-32 arginine vasopressin Rattus norvegicus 112-123 2992649-4 1985 When added 5 min after the onset of potassium stimulation, forskolin (1-80 microM) reduced the amount of vasopressin released during the remaining 5 min of stimulation. Colforsin 59-68 arginine vasopressin Rattus norvegicus 105-116 2984589-0 1985 Forskolin inhibits potassium-evoked release of vasopressin from rat neurohypophyses. Colforsin 0-9 arginine vasopressin Rattus norvegicus 47-58 2984589-1 1985 The effects of forskolin, an activator of adenylate cyclase, on the release of vasopressin from isolated rat neurointermediate lobes during a 10 min period of potassium stimulation were investigated. Colforsin 15-24 arginine vasopressin Rattus norvegicus 79-90 6889972-0 1982 Isoprenaline and forskolin increase evoked vasopressin release from rat pituitary. Colforsin 17-26 arginine vasopressin Rattus norvegicus 43-54 6889972-4 1982 Forskolin increased the vasopressin release by 98%. Colforsin 0-9 arginine vasopressin Rattus norvegicus 24-35 2995343-5 1985 These effects of glucagon can be mimicked by dibutyryl cyclic AMP or forskolin, suggesting that cyclic AMP augments both the resting Ca2+ and the vasopressin- or angiotensin II-stimulated influx. Colforsin 69-78 arginine vasopressin Rattus norvegicus 146-157 2982658-1 1985 Arginine-vasopressin (AVP) and lysine vasopressin (LVP) elicited a dose-dependent inhibition of noradrenaline-sensitive cyclic AMP accumulation in rat cerebral cortical slices, and of forskolin-stimulated adenylate cyclase activity in a rat cerebral cortical membrane preparation. Colforsin 184-193 arginine vasopressin Rattus norvegicus 9-20 2982658-1 1985 Arginine-vasopressin (AVP) and lysine vasopressin (LVP) elicited a dose-dependent inhibition of noradrenaline-sensitive cyclic AMP accumulation in rat cerebral cortical slices, and of forskolin-stimulated adenylate cyclase activity in a rat cerebral cortical membrane preparation. Colforsin 184-193 arginine vasopressin Rattus norvegicus 38-49 30074234-1 2018 INTRODUCTION: Melatonin was found to inhibit forskolin-stimulated oxytocin (OT) and vasopressin (VP) release in vitro. Colforsin 45-54 arginine vasopressin Rattus norvegicus 84-95 24802736-0 2014 Forskolin-stimulated vasopressin and oxytocin release from the rat hypothalamo-neurohypophysial system in vitro is inhibited by melatonin. Colforsin 0-9 arginine vasopressin Rattus norvegicus 21-32