PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2806756-1 1989 The effects of the selective muscarinic M1-receptor antagonist pirenzepine and the nonselective muscarinic antagonist atropine on bombesin- and peptone-stimulated release of pancreatic polypeptide (PP) were studied in healthy subjects. Atropine 118-126 gastrin releasing peptide Homo sapiens 130-138 2683738-4 1989 Atropine (500 micrograms, im) inhibited significantly (p less than 0.01) the gallbladder contraction (maximum contractile rate, 78.7 +/- 6.4%) in response to bombesin without any change of plasma CCK secretion, whereas proglumide (800 mg/day for 3 days, per os) decreased slightly but not significantly the gallbladder contraction, and had no effect on plasma CCK secretion. Atropine 0-8 gastrin releasing peptide Homo sapiens 158-166 2683738-6 1989 These findings suggest that atropine inhibits bombesin-induced gallbladder contraction, not via suppression of CCK release, but probably by inhibiting cholinergic mechanisms, whereas somatostatin inhibits gallbladder contraction, at least in part, by the suppression of bombesin-stimulated CCK secretion. Atropine 28-36 gastrin releasing peptide Homo sapiens 46-54 2888697-0 1987 Effect of atropine and somatostatin on bombesin-stimulated plasma immunoreactive trypsin release in man. Atropine 10-18 gastrin releasing peptide Homo sapiens 39-47 2834614-3 1988 The atropine-sensitive contraction and nonadrenergic noncholinergic relaxation in responses to FES which were tetrodotoxin-sensitive significantly increased in amplitude after bombesin. Atropine 4-12 gastrin releasing peptide Homo sapiens 176-184 2885900-6 1987 There were great differences between the effects of atropine and somatostatin on the hormonal responses to bombesin. Atropine 52-60 gastrin releasing peptide Homo sapiens 107-115 2885900-7 1987 Atropine slightly increased the response of gastrin by 19% and that of cholecystokinin by 15%, but strongly inhibited the bombesin-stimulated pancreatic polypeptide secretion by 97%. Atropine 0-8 gastrin releasing peptide Homo sapiens 122-130 3691621-1 1987 We have studied the effects of the selective muscarinic M1-receptor antagonist pirenzepine and the non-selective muscarinic antagonist atropine on bombesin- and peptone-stimulated gastrin release in healthy subjects. Atropine 135-143 gastrin releasing peptide Homo sapiens 147-155 2888697-1 1987 This study was undertaken to determine the effect of atropine and somatostatin, two inhibitors of intraduodenal pancreatic enzyme secretion, on bombesin-stimulated release of plasma immunoreactive trypsin in 6 healthy volunteers. Atropine 53-61 gastrin releasing peptide Homo sapiens 144-152 3976887-3 1985 Atropine at 1 mumol/l diminished the protein secretion in response to infusion of GRP at a dose of 1 nmol/l to 45% of control. Atropine 0-8 gastrin releasing peptide Homo sapiens 82-85 6647889-0 1983 The effect of atropine on bombesin and gastrin releasing peptide stimulated gastrin, pancreatic polypeptide and neurotensin release in man. Atropine 14-22 gastrin releasing peptide Homo sapiens 26-34 6647889-8 1983 Atropine blocked the release of PP during GRP and neurotensin infusion. Atropine 0-8 gastrin releasing peptide Homo sapiens 42-45 6647889-9 1983 Atropine had no effect on neurotensin or PP release during bombesin infusion, but did block the rise in plasma PP following bombesin infusion. Atropine 0-8 gastrin releasing peptide Homo sapiens 124-132 7433514-0 1980 Antagonism of the gut-contracting effects of bombesin and neurotensin by opioid peptides, morphine, atropine or tetrodotoxin. Atropine 100-108 gastrin releasing peptide Homo sapiens 45-53 7433514-1 1980 Morphine, met-enkephalin, beta-endorphin, tetrodotoxin (TTX), and atropine antagonized the gut-contracting effects of the peptides neurotensin and bombesin. Atropine 66-74 gastrin releasing peptide Homo sapiens 147-155