PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19841475-5	2010	The hM(1) receptor possessing a L430A/L431A double-point mutation was retained in the endoplasmic reticulum (ER), and atropine treatment caused the redistribution of the mutant receptor from the ER to the plasma membrane.	Atropine	118-126	cholinergic receptor muscarinic 1	Homo sapiens	4-9	
19841475-7	2010	The effect of atropine on the L430A/L431A receptor mutant suggests that L(430) and L(431) play a role in folding hM(1) receptors, which is necessary for exit from the ER.	Atropine	14-22	cholinergic receptor muscarinic 1	Homo sapiens	113-118	
19841475-8	2010	Using site-directed mutagenesis, we also identified amino acid residues at the base of transmembrane-spanning domain 1 (TM1), V(46) and L(47), that, when mutated, reduce the plasma membrane expression of hM(1) receptors in an atropine-reversible manner.	Atropine	226-234	cholinergic receptor muscarinic 1	Homo sapiens	204-209	
8905341-3	1996	Using recombinant human muscarinic acetylcholine receptors (m1 and m5) and the functional assay, receptor selection and amplification technology (R-SAT), we have now shown that co-administration of the full agonist, carbachol, and a competitive antagonist, atropine or pirenzepine, at fixed ratios display functional partial agonism.	Atropine	257-265	cholinergic receptor muscarinic 1	Homo sapiens	24-69