PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22496390-10 2012 We find significant accumulation of three oxysterols, 7alpha-hydroxycholesterol, 7beta-hydroxycholesterol, and 7-ketocholesterol, in mouse aortas of dyslipidemic ApoE-/- mice at the early stage of atherosclerosis. Oxysterols 42-52 apolipoprotein E Mus musculus 162-166 10720491-0 2000 Oxidized monocyte-derived macrophages in aortic atherosclerotic lesion from apolipoprotein E-deficient mice and from human carotid artery contain lipid peroxides and oxysterols. Oxysterols 166-176 apolipoprotein E Mus musculus 76-92 22785139-5 2012 Dietary oxysterol-induced plaque destabilization and rupture were blunted in ApoE(-/-) CCR2(-/-) mice. Oxysterols 8-17 apolipoprotein E Mus musculus 77-81 22785139-7 2012 These data indicate a primary role for monocyte-mediated inflammation via the MCP-1-CCR2 pathway and the resultant increase in MMP activity in plaque destabilization and rupture induced by dietary oxysterols in ApoE(-/-) mice. Oxysterols 197-207 apolipoprotein E Mus musculus 211-215 21412171-9 2011 In htau-ApoE mice on the high cholesterol regimen, brain oxysterol levels were less than in htau-ApoE mice, and the numbers of neurons with pathologically altered tau were similar to those in htau-ApoE mice on the high-cholesterol diet. Oxysterols 57-66 apolipoprotein E Mus musculus 8-12 11755924-0 2002 Oxysterol-induced activation of macrophage NADPH-oxidase enhances cell-mediated oxidation of LDL in the atherosclerotic apolipoprotein E deficient mouse: inhibitory role for vitamin E. Oxysterols 0-9 apolipoprotein E Mus musculus 120-136 2072040-9 1991 The stimulatory effect of HDL on apoE secretion can be clearly dissociated from cholesterol efflux; HDL stimulates apoE secretion from oxysterol-treated cells in the absence of measurable cholesterol efflux, while TNM-HDL promotes substantial cholesterol efflux from cholesterol-loaded cells but has no effect on apoE secretion. Oxysterols 135-144 apolipoprotein E Mus musculus 115-119 2072040-9 1991 The stimulatory effect of HDL on apoE secretion can be clearly dissociated from cholesterol efflux; HDL stimulates apoE secretion from oxysterol-treated cells in the absence of measurable cholesterol efflux, while TNM-HDL promotes substantial cholesterol efflux from cholesterol-loaded cells but has no effect on apoE secretion. Oxysterols 135-144 apolipoprotein E Mus musculus 115-119