PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34328253-15 2021 Unbound dolutegravir >= 431 nM induced expression of CYP3A4 (>= two-fold) in a dose-dependent manner, while 1.44 muM of unbound dolutegravir induced CYP2B6 expression 2.2 +- 0.3-fold (P = 0.0004). dolutegravir 8-20 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 149-155 34328253-15 2021 Unbound dolutegravir >= 431 nM induced expression of CYP3A4 (>= two-fold) in a dose-dependent manner, while 1.44 muM of unbound dolutegravir induced CYP2B6 expression 2.2 +- 0.3-fold (P = 0.0004). dolutegravir 128-140 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 149-155 32667979-2 2021 In a Phase 1 dolutegravir-efavirenz interaction study, mean dolutegravir Cmin decreased by 60% and 85% among CYP2B6 normal and slow/intermediate metabolizers, respectively. dolutegravir 13-25 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 109-115 32960272-0 2021 CYP2B6 Genotype and Weight Gain Differences Between Dolutegravir and Efavirenz. dolutegravir 52-64 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 0-6 35099526-0 2022 Corrigendum to: CYP2B6 Genotype and Weight Gain Differences Between Dolutegravir and Efavirenz. dolutegravir 68-80 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 16-22