PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31478469-0 2019 Reduced soluble CD14 levels after switching from a dual regimen with lamivudine plus boosted protease inhibitors to lamivudine plus dolutegravir in virologically suppressed HIV-infected patients. dolutegravir 132-144 CD14 molecule Homo sapiens 16-20 34120186-0 2021 Switching from boosted PIs to dolutegravir decreases soluble CD14 and adiponectin in high cardiovascular risk people living with HIV. dolutegravir 30-42 CD14 molecule Homo sapiens 61-65 34120186-5 2021 Soluble CD14 (-11%, P < 0.001) and adiponectin (-11%, P < 0.001) significantly declined and high-sensitive C-reactive protein (-13%, P = 0.069) and oxidized LDL (-13%, P = 0.084) tended to decrease with dolutegravir. dolutegravir 203-215 CD14 molecule Homo sapiens 8-12 34120186-6 2021 Switching to dolutegravir remained significantly associated with soluble CD14 and adiponectin reductions after adjustment for baseline variables. dolutegravir 13-25 CD14 molecule Homo sapiens 73-77 34120186-8 2021 CONCLUSIONS: Switching from boosted PIs to dolutegravir in PLWH with high cardiovascular risk led to soluble CD14 and adiponectin reductions at 48 weeks. dolutegravir 43-55 CD14 molecule Homo sapiens 109-113 35551149-7 2022 RESULTS: Through Week 48, changes in biomarkers did not significantly differ between dolutegravir + rilpivirine and CAR groups, except for increases in soluble CD14 and decreases in fatty acid binding protein-2, which favored dolutegravir + rilpivirine. dolutegravir 85-97 CD14 molecule Homo sapiens 160-164