PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21381981-3 2011 S/GSK1349572 represents a new INI in current development. dolutegravir 2-12 PHD finger protein 5A Homo sapiens 30-33 25924475-5 2015 Comparing the two INIs as the "anchor" for HAART, DTG exhibited an equivalent CI to that of RAL on wild type HIV-1 replication; but a greater synergy than RAL on INI-resistant HIV-1 replication. dolutegravir 50-53 PHD finger protein 5A Homo sapiens 18-21 29957545-1 2018 BACKGROUND: Dolutegravir (DTG) is a next-generation HIV integrase inhibitor (INI) with an increased genetic barrier to resistance with respect to raltegravir (RAL) or elvitegravir (EVG). dolutegravir 12-24 PHD finger protein 5A Homo sapiens 77-80 29957545-1 2018 BACKGROUND: Dolutegravir (DTG) is a next-generation HIV integrase inhibitor (INI) with an increased genetic barrier to resistance with respect to raltegravir (RAL) or elvitegravir (EVG). dolutegravir 26-29 PHD finger protein 5A Homo sapiens 77-80 25397500-0 2014 Use of dolutegravir in two INI-experienced patients with multiclass resistance resulted in excellent virological and immunological responses. dolutegravir 7-19 PHD finger protein 5A Homo sapiens 27-30 21381981-10 2011 EXPERT OPINION: S/GSK1349572 represents a new, unboosted, once-daily INI in development with distinct pharmacokinetics and resistance profile, which has showed promising potency and tolerability in the first clinical studies. dolutegravir 18-28 PHD finger protein 5A Homo sapiens 9-12 22101373-11 2011 Global phase III clinical trials of dolutegravir (DTG), a second generation INI, are currently in progress. dolutegravir 36-48 PHD finger protein 5A Homo sapiens 76-79 22101373-11 2011 Global phase III clinical trials of dolutegravir (DTG), a second generation INI, are currently in progress. dolutegravir 50-53 PHD finger protein 5A Homo sapiens 76-79