PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32087256-6 2020 Z-guggulsterone reduced the co-activator SRC-1 expression in hBDMECs, as to prevent the activation of MDR1 gene transcription. pregna-4,17-diene-3,16-dione 0-15 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 41-46 23920124-0 2013 Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling. pregna-4,17-diene-3,16-dione 0-13 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 116-119 23119029-6 2012 Treatment with guggulsterone and GW4064 also caused dose-dependent changes in Src (Tyr416) phosphorylation. pregna-4,17-diene-3,16-dione 15-28 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 78-81 23119029-8 2012 Moreover, guggulsterone-induced EGFR and ERK phosphorylation and cell proliferation were abolished by inhibiting activation of Src, EGFR and MEK. pregna-4,17-diene-3,16-dione 10-23 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 127-130