PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29453451-0 2018 Prevalence and impact of baseline resistance-associated substitutions on the efficacy of ledipasvir/sofosbuvir or simeprevir/sofosbuvir against GT1 HCV infection. Simeprevir 114-124 beta-1,4-galactosyltransferase 1 Homo sapiens 144-147 30070722-12 2018 Conclusions: In treatment-naive subjects without cirrhosis, AL-335 + odalasvir + simeprevir for 6-8 weeks was generally safe and highly efficacious against HCV GT1. Simeprevir 81-91 beta-1,4-galactosyltransferase 1 Homo sapiens 160-163 30145562-1 2018 INTRODUCTION AND AIM: Approximately 10%-15% of patients with hepatitis C genotype 1 (HCV GT1) experience virological relapse after all-oral antiviral regimen using simeprevir (SMV) and sofosbuvir (SOF). Simeprevir 164-174 beta-1,4-galactosyltransferase 1 Homo sapiens 89-92 30145562-1 2018 INTRODUCTION AND AIM: Approximately 10%-15% of patients with hepatitis C genotype 1 (HCV GT1) experience virological relapse after all-oral antiviral regimen using simeprevir (SMV) and sofosbuvir (SOF). Simeprevir 176-179 beta-1,4-galactosyltransferase 1 Homo sapiens 89-92 30145562-13 2018 CONCLUSIONS: Treatment with LDV/SOF with/without RBV for 12-24 weeks was very well tolerated and resulted in high SVR 12 rates (96%) in HCV GT1 relapsers to SMV + SOF treatment. Simeprevir 157-160 beta-1,4-galactosyltransferase 1 Homo sapiens 140-143 26096332-2 2015 Combined simeprevir (SMV) and sofosbuvir (SOF) with or without ribavirin (RBV) results in high sustained virological response (SVR) rates along with minimal adverse events (AEs) in patients with hepatitis C genotype 1 (HCV GT1). Simeprevir 9-19 beta-1,4-galactosyltransferase 1 Homo sapiens 223-226 26096332-2 2015 Combined simeprevir (SMV) and sofosbuvir (SOF) with or without ribavirin (RBV) results in high sustained virological response (SVR) rates along with minimal adverse events (AEs) in patients with hepatitis C genotype 1 (HCV GT1). Simeprevir 21-24 beta-1,4-galactosyltransferase 1 Homo sapiens 223-226