PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21726384-6 2011 In addition, we provide data which indicate that the cdd1 mutation negatively regulates the npr1 mutation-induced hyperactivation of ethylene/jasmonic acid signalling. jasmonic acid 142-155 regulatory protein (NPR1) Arabidopsis thaliana 92-96 32265961-3 2020 The NPR1 gene has also been shown to be involved in the crosstalk between SAR signaling and the jasmonic acid-ethylene (JA/Et) pathway, which is involved in the response to necrotrophic fungi. jasmonic acid 96-109 regulatory protein (NPR1) Arabidopsis thaliana 4-8 22213815-8 2012 Furthermore, NPR1 was found to be a positive regulator of JA-induced expression of MDHAR3 and TAT3. jasmonic acid 58-60 regulatory protein (NPR1) Arabidopsis thaliana 13-17 32481026-13 2014 Although NPR1 is involved in the cross-talk between the salicylic acid, jasmonic acid and ethylene pathways, understanding the nematode resistance mechanism in plants is still imprecise. jasmonic acid 72-85 regulatory protein (NPR1) Arabidopsis thaliana 9-13 23071821-2 2012 Here we demonstrate that P6 additionally acts as a pathogenicity effector of an unique and novel type, modifying NPR1 (a key regulator of salicylic acid (SA)- and jasmonic acid (JA)-dependent signaling) and inhibiting SA-dependent defence responses We find that that transgene-mediated expression of P6 in Arabidopsis and transient expression in Nicotiana benthamiana has profound effects on defence signaling, suppressing expression of representative SA-responsive genes and increasing expression of representative JA-responsive genes. jasmonic acid 163-176 regulatory protein (NPR1) Arabidopsis thaliana 113-117 23071821-2 2012 Here we demonstrate that P6 additionally acts as a pathogenicity effector of an unique and novel type, modifying NPR1 (a key regulator of salicylic acid (SA)- and jasmonic acid (JA)-dependent signaling) and inhibiting SA-dependent defence responses We find that that transgene-mediated expression of P6 in Arabidopsis and transient expression in Nicotiana benthamiana has profound effects on defence signaling, suppressing expression of representative SA-responsive genes and increasing expression of representative JA-responsive genes. jasmonic acid 178-180 regulatory protein (NPR1) Arabidopsis thaliana 113-117 21722410-1 2011 In Arabidopsis, non-expressor of pathogenesis related genes-1, NPR1 has been shown to be a positive regulator of the salicylic acid controlled systemic acquired resistance pathway and modulates the cross talk between SA and JA signaling. jasmonic acid 224-226 regulatory protein (NPR1) Arabidopsis thaliana 63-67 17510065-1 2007 Cytosolic NPR1 has been shown to be essential for the salicylic acid (SA)-mediated suppression of jasmonic acid (JA)-responsive gene expression. jasmonic acid 98-111 regulatory protein (NPR1) Arabidopsis thaliana 10-14 20521949-3 2010 Disease resistance was enhanced in transgenic wheat and Arabidopsis plants that constitutively overexpress the NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1) gene, which regulates salicylic acid (SA) signaling and modulates the activation of jasmonic acid (JA)-dependent defenses. jasmonic acid 247-260 regulatory protein (NPR1) Arabidopsis thaliana 111-155 20521949-3 2010 Disease resistance was enhanced in transgenic wheat and Arabidopsis plants that constitutively overexpress the NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1) gene, which regulates salicylic acid (SA) signaling and modulates the activation of jasmonic acid (JA)-dependent defenses. jasmonic acid 247-260 regulatory protein (NPR1) Arabidopsis thaliana 157-161 20521949-3 2010 Disease resistance was enhanced in transgenic wheat and Arabidopsis plants that constitutively overexpress the NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1) gene, which regulates salicylic acid (SA) signaling and modulates the activation of jasmonic acid (JA)-dependent defenses. jasmonic acid 262-264 regulatory protein (NPR1) Arabidopsis thaliana 111-155 20521949-3 2010 Disease resistance was enhanced in transgenic wheat and Arabidopsis plants that constitutively overexpress the NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1) gene, which regulates salicylic acid (SA) signaling and modulates the activation of jasmonic acid (JA)-dependent defenses. jasmonic acid 262-264 regulatory protein (NPR1) Arabidopsis thaliana 157-161 19716624-5 2010 NPR1 also positively regulates SA tolerance and plays a role in SA-mediated negative regulation of jasmonic acid (JA) signaling. jasmonic acid 99-112 regulatory protein (NPR1) Arabidopsis thaliana 0-4 19716624-5 2010 NPR1 also positively regulates SA tolerance and plays a role in SA-mediated negative regulation of jasmonic acid (JA) signaling. jasmonic acid 114-116 regulatory protein (NPR1) Arabidopsis thaliana 0-4 20836879-0 2010 OCP3 is an important modulator of NPR1-mediated jasmonic acid-dependent induced defenses in Arabidopsis. jasmonic acid 48-61 regulatory protein (NPR1) Arabidopsis thaliana 34-38 20836879-8 2010 In addition, we provide evidence showing that the over-expression of an engineered cytosolic isoform of the disease resistance regulator NPR1 restores the impaired JA-induced disease resistance in ocp3 plants. jasmonic acid 164-166 regulatory protein (NPR1) Arabidopsis thaliana 137-141 20836879-9 2010 CONCLUSIONS: Our findings point to a model in which OCP3 may modulate the nucleocytosolic function of NPR1 in the regulation of JA-dependent induced defense responses. jasmonic acid 128-130 regulatory protein (NPR1) Arabidopsis thaliana 102-106 19176718-3 2009 In Arabidopsis (Arabidopsis thaliana), NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) was demonstrated to be required for SA-mediated suppression of JA-dependent defenses. jasmonic acid 153-155 regulatory protein (NPR1) Arabidopsis thaliana 39-82 19176718-3 2009 In Arabidopsis (Arabidopsis thaliana), NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) was demonstrated to be required for SA-mediated suppression of JA-dependent defenses. jasmonic acid 153-155 regulatory protein (NPR1) Arabidopsis thaliana 84-88 19176718-8 2009 Furthermore, JA-dependent resistance against biotic attackers was antagonized by SA in an NPR1-dependent fashion only when the plant-attacker combination did not result in the production of high levels of endogenous ET. jasmonic acid 13-15 regulatory protein (NPR1) Arabidopsis thaliana 90-94 19176718-10 2009 Our results suggest a model in which ET modulates the NPR1 dependency of SA-JA antagonism, possibly to compensate for enhanced allocation of NPR1 to function in SA-dependent activation of PR genes. jasmonic acid 76-78 regulatory protein (NPR1) Arabidopsis thaliana 54-58 18397206-2 2008 AtNPR1 also modulates SA-induced suppression of jasmonic acid-responsive gene expression, and npr1 mutants manifest enhanced herbivore resistance. jasmonic acid 48-61 regulatory protein (NPR1) Arabidopsis thaliana 0-6 17510065-8 2007 Our results demonstrate that WRKY62 acts downstream of cytosolic NPR1 and negatively regulates JA-responsive gene expression, suggesting that WRKY62 may be involved in the SA-mediated suppression of JA signaling. jasmonic acid 95-97 regulatory protein (NPR1) Arabidopsis thaliana 65-69 17510065-1 2007 Cytosolic NPR1 has been shown to be essential for the salicylic acid (SA)-mediated suppression of jasmonic acid (JA)-responsive gene expression. jasmonic acid 113-115 regulatory protein (NPR1) Arabidopsis thaliana 10-14 17510065-2 2007 However, factors downstream of NPR1 in the cross-talk between SA and JA signaling are unclear. jasmonic acid 69-71 regulatory protein (NPR1) Arabidopsis thaliana 31-35 15337097-1 2004 Recent work has shown that the Arabidopsis NPR1 protein not only plays an essential role in salicylic acid (SA)-mediated systemic acquired resistance and rhizobacterium-triggered induced systemic resistance, but also is involved in crosstalk inhibition of jasmonic acid (JA)-mediated defense responses. jasmonic acid 256-269 regulatory protein (NPR1) Arabidopsis thaliana 43-47 16325410-5 2005 Expression analysis of SEN1 in a number of defence signalling mutants indicated that activation of this gene by pathogen occurs predominantly via the salicylic and jasmonic acid signalling pathways, involving the functions of EDS5, NPR1 and JAR1. jasmonic acid 164-177 regulatory protein (NPR1) Arabidopsis thaliana 232-236 16176083-5 2005 As a cross-talk point of a variety of defense signaling pathways, probably through direct or indirect interacting with some WRKY TFs and a NPR1-like protein NPR4, NPR1 is essential in balancing salicylic acid- and jasmonic acid- dependent signal transduction pathways, which is achieved through an unknown mechanism in the cytosol. jasmonic acid 214-227 regulatory protein (NPR1) Arabidopsis thaliana 139-143 16176083-5 2005 As a cross-talk point of a variety of defense signaling pathways, probably through direct or indirect interacting with some WRKY TFs and a NPR1-like protein NPR4, NPR1 is essential in balancing salicylic acid- and jasmonic acid- dependent signal transduction pathways, which is achieved through an unknown mechanism in the cytosol. jasmonic acid 214-227 regulatory protein (NPR1) Arabidopsis thaliana 163-167 15337097-1 2004 Recent work has shown that the Arabidopsis NPR1 protein not only plays an essential role in salicylic acid (SA)-mediated systemic acquired resistance and rhizobacterium-triggered induced systemic resistance, but also is involved in crosstalk inhibition of jasmonic acid (JA)-mediated defense responses. jasmonic acid 271-273 regulatory protein (NPR1) Arabidopsis thaliana 43-47 12615947-4 2003 Analysis of the Arabidopsis mutant npr1, which is impaired in SA signal transduction, revealed that the antagonistic effect of SA on JA signaling requires the regulatory protein NPR1. jasmonic acid 133-135 regulatory protein (NPR1) Arabidopsis thaliana 35-39 15231270-4 2004 Apart from its role in regulating SAR in the nucleus, a novel cytosolic function of NPR1 in cross-communication between SA- and JA-dependent defense signaling pathways has been identified. jasmonic acid 128-130 regulatory protein (NPR1) Arabidopsis thaliana 84-88 12848424-0 2003 Ethylene and jasmonic acid signaling affect the NPR1-independent expression of defense genes without impacting resistance to Pseudomonas syringae and Peronospora parasitica in the Arabidopsis ssi1 mutant. jasmonic acid 13-26 regulatory protein (NPR1) Arabidopsis thaliana 48-52 12848424-8 2003 In the present study, we show that, in addition to SA, ethylene and JA signaling also are required for the ssi1-conferred constitutive expression of PDF1.2 and the NPR1-independent expression of PR-1. jasmonic acid 68-70 regulatory protein (NPR1) Arabidopsis thaliana 164-168 14507997-8 2003 In parallel with the loss of ssi2-conferred constitutive SA signaling, the ability of jasmonic acid to activate PDF1.2 expression is reinstated in the sfd1 ssi2 npr1 plant. jasmonic acid 86-99 regulatory protein (NPR1) Arabidopsis thaliana 161-165 12615947-0 2003 NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol. jasmonic acid 50-59 regulatory protein (NPR1) Arabidopsis thaliana 0-4 12615947-4 2003 Analysis of the Arabidopsis mutant npr1, which is impaired in SA signal transduction, revealed that the antagonistic effect of SA on JA signaling requires the regulatory protein NPR1. jasmonic acid 133-135 regulatory protein (NPR1) Arabidopsis thaliana 178-182 12615947-5 2003 Nuclear localization of NPR1, which is essential for SA-mediated defense gene expression, is not required for the suppression of JA signaling, indicating that cross-talk between SA and JA is modulated through a novel function of NPR1 in the cytosol. jasmonic acid 185-187 regulatory protein (NPR1) Arabidopsis thaliana 24-28 12615947-5 2003 Nuclear localization of NPR1, which is essential for SA-mediated defense gene expression, is not required for the suppression of JA signaling, indicating that cross-talk between SA and JA is modulated through a novel function of NPR1 in the cytosol. jasmonic acid 185-187 regulatory protein (NPR1) Arabidopsis thaliana 229-233 9927638-8 1999 Interestingly, expression of PDF1.2, which previously has been shown to be SA independent but jasmonic acid and ethylene dependent, was also suppressed in ssi1 npr1-5 plants by the nahG gene. jasmonic acid 94-107 regulatory protein (NPR1) Arabidopsis thaliana 160-164 12028576-5 2002 Expression of the ET/JA-responsive PDF1.2 gene was markedly reduced in hrl1 npr1 and in SA-depleted hrl1 nahG plants. jasmonic acid 21-23 regulatory protein (NPR1) Arabidopsis thaliana 76-80 9724702-7 1998 Hence, we postulate that rhizobacteria-mediated ISR follows a novel signaling pathway in which components from the jasmonate and ethylene response are engaged successively to trigger a defense reaction that, like SAR, is regulated by NPR1. jasmonic acid 115-124 regulatory protein (NPR1) Arabidopsis thaliana 234-238