PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26427870-0 2015 Therapeutic effects of antibiotic drug tigecycline against cervical squamous cell carcinoma by inhibiting Wnt/beta-catenin signaling. Tigecycline 39-50 catenin beta 1 Homo sapiens 110-122 26427870-2 2015 We show that tigecycline, a FDA-approved antibiotic drug, targets cervical squamous cell carcinoma through inhibiting Wnt/beta-catenin signaling pathway. Tigecycline 13-24 catenin beta 1 Homo sapiens 122-134 26427870-6 2015 We further show that tigecycline decreases level of both cytoplasmic and nuclear beta-catenin and suppressed Wnt/beta-catenin-mediated transcription through increasing levels of Axin 1 in Hela cells. Tigecycline 21-32 catenin beta 1 Homo sapiens 81-93 26427870-6 2015 We further show that tigecycline decreases level of both cytoplasmic and nuclear beta-catenin and suppressed Wnt/beta-catenin-mediated transcription through increasing levels of Axin 1 in Hela cells. Tigecycline 21-32 catenin beta 1 Homo sapiens 113-125 26427870-7 2015 In addition, stabilization or overexpression of beta-catenin using pharmacological and genetic approaches abolished the effects of tigecycline in inhibiting proliferation and inducing apoptosis of Hela cells. Tigecycline 131-142 catenin beta 1 Homo sapiens 48-60