PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15525791-9 2005 Taken together, these results suggest that ethyl pyruvate inhibits DNA-binding by covalently modifying p65 at Cys(38). ethyl pyruvate 43-57 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 103-106 31677497-6 2019 In addition, EP decreased microglia enrichment in myelin sheath, and declined TLR4/p-NF-kb/p65 and IL-1beta and IL-6, inhibiting microglia-mediated neuroinflammation. ethyl pyruvate 13-15 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 91-94 23891677-0 2013 Up-down regulation of HO-1 and iNOS gene expressions by ethyl pyruvate via recruiting p300 to Nrf2 and depriving It from p65. ethyl pyruvate 56-70 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 121-124 15525791-0 2005 Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65. ethyl pyruvate 0-14 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 88-91 15525791-10 2005 We conclude that some of the beneficial anti-inflammatory effects of ethyl pyruvate may be due to modification of p65, thereby inhibiting signaling via the NF-kappaB pathway. ethyl pyruvate 69-83 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 114-117