PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31677497-6 2019 In addition, EP decreased microglia enrichment in myelin sheath, and declined TLR4/p-NF-kb/p65 and IL-1beta and IL-6, inhibiting microglia-mediated neuroinflammation. ethyl pyruvate 13-15 interleukin 6 Mus musculus 112-116 24498418-9 2014 CONCLUSION: Taken together, these results indicated that ethyl pyruvate protected against Con A-induced autoimmune hepatitis by decreasing both early (TNF-alpha, IL-2, IL-1beta and IL-6) and late (HMGB1) cytokine expression in mice. ethyl pyruvate 57-71 interleukin 6 Mus musculus 181-185 24498418-7 2014 Pretreatment with ethyl pyruvate ameliorated the pathological effects of Con A-induced autoimmune hepatitis and significantly decreased the levels of TNF-alpha, IL-2, IL-6 and IL-1beta at 3h and 6h and the level of HMGB1 at 6h and 24h post injection. ethyl pyruvate 18-32 interleukin 6 Mus musculus 167-171 24453420-9 2013 Furthermore, ethyl pyruvate inhibited the HMGB1/TLR4/ NF-kappab axis and the release of cytokines (TNF-alpha and IL-6). ethyl pyruvate 13-27 interleukin 6 Mus musculus 113-117