PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27838489-9	2017	HMGB1 inhibition by ethyl pyruvate or blockade by neutralizing antibodies significantly decreased the phosphorylation of STAT3, p38 and IkappaBalpha, the production of IL-1beta and TNF-alpha, and the islet injury in wild-type islets after exposure to H/R and significantly improved early islet graft failure.	ethyl pyruvate	20-34	mitogen-activated protein kinase 14	Homo sapiens	128-131	
34289368-5	2021	HMGB1 release inhibition using ethyl pyruvate (EP) and glycyrrhizic acid (GA) prevents TauO-induced senescence through inhibition of p38-mitogen-activated protein kinase (MAPK) and nuclear factor kappaB (NF-kappaB)-the essential signaling pathways for SASP development.	ethyl pyruvate	31-45	mitogen-activated protein kinase 14	Homo sapiens	133-169	
34289368-5	2021	HMGB1 release inhibition using ethyl pyruvate (EP) and glycyrrhizic acid (GA) prevents TauO-induced senescence through inhibition of p38-mitogen-activated protein kinase (MAPK) and nuclear factor kappaB (NF-kappaB)-the essential signaling pathways for SASP development.	ethyl pyruvate	31-45	mitogen-activated protein kinase 14	Homo sapiens	171-175	
34289368-5	2021	HMGB1 release inhibition using ethyl pyruvate (EP) and glycyrrhizic acid (GA) prevents TauO-induced senescence through inhibition of p38-mitogen-activated protein kinase (MAPK) and nuclear factor kappaB (NF-kappaB)-the essential signaling pathways for SASP development.	ethyl pyruvate	47-49	mitogen-activated protein kinase 14	Homo sapiens	133-169	
34289368-5	2021	HMGB1 release inhibition using ethyl pyruvate (EP) and glycyrrhizic acid (GA) prevents TauO-induced senescence through inhibition of p38-mitogen-activated protein kinase (MAPK) and nuclear factor kappaB (NF-kappaB)-the essential signaling pathways for SASP development.	ethyl pyruvate	47-49	mitogen-activated protein kinase 14	Homo sapiens	171-175