PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34078225-7 2021 The levels of HS-activated autophagy-regulatory proteins were affected by EP, in which the phosphorylated mTOR and AKT were reduced, and the phosphorylated AMPK increased, accompanied with upregulation in ULK1, Atg7, Atg12 and LC3II, and downregulation of p62.Conclusion: In conclusion, EP ameliorated HS-induced inflammatory responses and MOD, and the underlying mechanism is associated with the induction of the stress proteins HO-1 and HSP70 as well as restorage of autophagy. ethyl pyruvate 287-289 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 156-160