PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18777173-4	2009	CONCLUSIONS: Miconazole oral gel and oral voriconazole produced comparable increase in the exposure to etoricoxib, presumably via CYP3A inhibition.	Etoricoxib	103-113	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	130-135	
11353749-10	2001	Moreover, etoricoxib (0.1-100 microM) was found to be a relatively weak inhibitor (IC(50) > 100 microM) of multiple P450s (CYP1A2, CYP2D6, CYP3A, CYP2E1, CYP2C9, and CYP2C19) in human liver microsomes.	Etoricoxib	10-20	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	142-147	
17999057-8	2008	All are eliminated by hepatic metabolism involving mainly CYP2C9 (celecoxib, lumiracoxib) and CYP3A4 (etoricoxib).	Etoricoxib	102-112	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	94-100	
15342613-0	2004	The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.	Etoricoxib	72-82	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	33-51	
15342613-0	2004	The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.	Etoricoxib	72-82	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	53-58	
15342613-1	2004	To investigate the influence of modifying in vivo cytochrome P450 3A (CYP3A) activity on the pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, and of etoricoxib administration on CYP3A activity, a 3-part, randomized, crossover study was conducted in 3 panels of healthy volunteers.	Etoricoxib	113-123	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	50-68	
15342613-1	2004	To investigate the influence of modifying in vivo cytochrome P450 3A (CYP3A) activity on the pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, and of etoricoxib administration on CYP3A activity, a 3-part, randomized, crossover study was conducted in 3 panels of healthy volunteers.	Etoricoxib	113-123	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	70-75