PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10900685-5	2000	A significant correlation was found between AChE activity and the level of the primary products of oxidation in blood erythrocytes of AD patients before and after therapy with amiridine and gliatiline.	amiridine	176-185	acetylcholinesterase (Cartwright blood group)	Homo sapiens	44-48	
33728848-1	2021	OBJECTIVE: To evaluate the efficacy of the AChE inhibitor ipidacrine when added to traditional therapy in outpatients with tunnel syndromes (TS) based on clinical, neurophysiological and psycho-emotional indicators.	amiridine	58-68	acetylcholinesterase (Cartwright blood group)	Homo sapiens	43-47	
11508499-5	2001	There was a statistically significant relationship between ACE activity and the levels of primary oxidation products in the RBC of patients with AD before and after treatment with amiridine and gliatiline.	amiridine	180-189	acetylcholinesterase (Cartwright blood group)	Homo sapiens	59-62	
25202788-5	2014	In this connection, the efficacy of acetylcholinesterase inhibitors: galantamine (reminil),neuromidin, rivastigmine in the treatment of PD patients with dementia is discussed.	amiridine	91-101	acetylcholinesterase (Cartwright blood group)	Homo sapiens	36-56	
11256231-4	2000	The order of inhibitory potency (IC50) towards AChE activity under optimal assay conditions for each ChE inhibitor was: physostigmine (0.67 nM) > rivastigmine (4.3 nM) > donepezil (6.7 nM) > TAK-147 (12 nM) > tacrine (77 nM) > ipidacrine (270 nM).	amiridine	227-237	acetylcholinesterase (Cartwright blood group)	Homo sapiens	47-51	
9062656-2	1997	AChE inhibitors, including physostigmine, E-2020, amiridin, tetrahydroaminoacridine (THA) and Nicergoline had a poor effect on AChE present in the senile plaque-rich fraction isolated from Alzheimer brain than that either in the soluble fraction of Alzheimer brain or in the control brain.	amiridine	50-58	acetylcholinesterase (Cartwright blood group)	Homo sapiens	0-4	
9228650-2	1997	NIK-247, tacrine and E-2020 all strongly inhibited acetylcholinesterase (AChE) in human red blood cells (IC50s = 1.0 x 10(-6), 2.9 x 10(-7) and 3.7 x 10(-8) M, respectively).	amiridine	0-7	acetylcholinesterase (Cartwright blood group)	Homo sapiens	51-71	
9228650-2	1997	NIK-247, tacrine and E-2020 all strongly inhibited acetylcholinesterase (AChE) in human red blood cells (IC50s = 1.0 x 10(-6), 2.9 x 10(-7) and 3.7 x 10(-8) M, respectively).	amiridine	0-7	acetylcholinesterase (Cartwright blood group)	Homo sapiens	73-77	
9228650-5	1997	Moreover, the inhibitory effect of NIK-247 on AChE was reversible.	amiridine	35-42	acetylcholinesterase (Cartwright blood group)	Homo sapiens	46-50	
7536306-5	1994	The acetylcholinesterase inhibitor, physostigmine, exerts a similar modulatory influence on the ACh current and on its extinction, and also prevents the manifestation of the effects of amiridin and tacrine.	amiridine	185-193	acetylcholinesterase (Cartwright blood group)	Homo sapiens	4-24	
35548968-1	2022	AIM: To evaluate the efficacy of combination of alpha-lipoic acid and acetylcholinesterase inhibitor (ipidacrine hydrochloride) to prevent the development and improve the course of paclitaxel-induced peripheral neuropathy (PIPN) in patients with breast cancer according to the Total Neuropathy Score.	amiridine	102-126	acetylcholinesterase (Cartwright blood group)	Homo sapiens	70-90	
35548968-7	2022	RESULTS: The use of alpha-lipoic acid in combination with an acetylcholinesterase inhibitor (ipidacrine hydrochloride) significantly reduces the symptoms and severity of PIPN.	amiridine	93-117	acetylcholinesterase (Cartwright blood group)	Homo sapiens	61-81