PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32537715-3 2020 The primary objective of this study was to evaluate the effects of repeated doses of fedratinib on the activity of CYP2D6, CYP2C19, and CYP3A4 in patients with solid tumors using a CYP probe cocktail. Fedratinib 85-95 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 123-130 32537715-8 2020 CONCLUSION: Fedratinib is a weak inhibitor of CYP2D6, and a moderate inhibitor of CYP2C19 and CYP3A4. Fedratinib 12-22 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 82-89