PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35001806-9 2022 Further, we show that safinamide treatment resulted in decreased mRNA and protein expressions of p21 and plasminogen activator inhibitor-1 (PAI-1). safinamide 22-32 cyclin dependent kinase inhibitor 1A Homo sapiens 97-100 35001806-10 2022 Moreover, silencing of Sirtuin1 (SIRT1) abolished the effects of safinamide on the mRNA levels of p21 and PAI-1, as well as SA-beta-gal-positive cells in Abeta1-42 oligomers-induced M17 cells. safinamide 65-75 cyclin dependent kinase inhibitor 1A Homo sapiens 98-101