PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33064293-0	2021	Impact of Human SULT1E1 Polymorphisms on the Sulfation of 17beta-Estradiol, 4-Hydroxytamoxifen, and Diethylstilbestrol by SULT1E1 Allozymes.	afimoxifene	76-94	sulfotransferase family 1E member 1	Homo sapiens	16-23	
33064293-0	2021	Impact of Human SULT1E1 Polymorphisms on the Sulfation of 17beta-Estradiol, 4-Hydroxytamoxifen, and Diethylstilbestrol by SULT1E1 Allozymes.	afimoxifene	76-94	sulfotransferase family 1E member 1	Homo sapiens	122-129	
33064293-1	2021	BACKGROUND AND OBJECTIVES: Previous studies have revealed that sulfation, as mediated by the estrogen-sulfating cytosolic sulfotransferase (SULT) SULT1E1, is involved in the metabolism of 17beta-estradiol (E2), 4-hydroxytamoxifen (4OH-tamoxifen), and diethylstilbestrol in humans.	afimoxifene	211-229	sulfotransferase family 1E member 1	Homo sapiens	146-153	
33064293-1	2021	BACKGROUND AND OBJECTIVES: Previous studies have revealed that sulfation, as mediated by the estrogen-sulfating cytosolic sulfotransferase (SULT) SULT1E1, is involved in the metabolism of 17beta-estradiol (E2), 4-hydroxytamoxifen (4OH-tamoxifen), and diethylstilbestrol in humans.	afimoxifene	231-244	sulfotransferase family 1E member 1	Homo sapiens	146-153	
33064293-3	2021	METHODS: In this study, five missense coding single nucleotide polymorphisms of the SULT1E1 gene were selected to investigate the sulfating activity of the coded SULT1E1 allozymes toward E2, 4OH-tamoxifen, and diethylstilbestrol.	afimoxifene	191-204	sulfotransferase family 1E member 1	Homo sapiens	84-91	
33064293-3	2021	METHODS: In this study, five missense coding single nucleotide polymorphisms of the SULT1E1 gene were selected to investigate the sulfating activity of the coded SULT1E1 allozymes toward E2, 4OH-tamoxifen, and diethylstilbestrol.	afimoxifene	191-204	sulfotransferase family 1E member 1	Homo sapiens	162-169	
33064293-5	2021	RESULTS: Purified SULT1E1 allozymes were shown to display differential sulfating activities toward E2, 4OH-tamoxifen, and diethylstilbestrol.	afimoxifene	103-116	sulfotransferase family 1E member 1	Homo sapiens	18-25	
33064293-6	2021	Kinetic analysis revealed further distinct Km (reflecting substrate affinity) and Vmax (reflecting catalytic activity) values of the five SULT1E1 allozymes with E2, 4OH-tamoxifen, and diethylstilbestrol as substrates.	afimoxifene	165-178	sulfotransferase family 1E member 1	Homo sapiens	138-145